Hu L - Search Results

1

Danthron functions as a retinoic X receptor antagonist by stabilizing tetramers of the receptor.

Zhang H, Zhou R, Li L, Chen J, Chen L, Li C, Ding H, Yu L, Hu L, Jiang H, Shen X. Zhang H, et al. Among authors: hu l. J Biol Chem. 2011 Jan 21;286(3):1868-75. doi: 10.1074/jbc.M110.166215. Epub 2010 Nov 17. J Biol Chem. 2011. PMID: 21084305 Free PMC article.

2

Structure basis of bigelovin as a selective RXR agonist with a distinct binding mode.

Zhang H, Li L, Chen L, Hu L, Jiang H, Shen X. Zhang H, et al. Among authors: hu l. J Mol Biol. 2011 Mar 18;407(1):13-20. doi: 10.1016/j.jmb.2011.01.032. Epub 2011 Jan 22. J Mol Biol. 2011. PMID: 21262235

3

Molecular determinants of magnolol targeting both RXRα and PPARγ.

Zhang H, Xu X, Chen L, Chen J, Hu L, Jiang H, Shen X. Zhang H, et al. Among authors: hu l. PLoS One. 2011;6(11):e28253. doi: 10.1371/journal.pone.0028253. Epub 2011 Nov 29. PLoS One. 2011. PMID: 22140563 Free PMC article.

4

Structural Basis for Small Molecule NDB (N-Benzyl-N-(3-(tert-butyl)-4-hydroxyphenyl)-2,6-dichloro-4-(dimethylamino) Benzamide) as a Selective Antagonist of Farnesoid X Receptor α (FXRα) in Stabilizing the Homodimerization of the Receptor.

Xu X, Xu X, Liu P, Zhu ZY, Chen J, Fu HA, Chen LL, Hu LH, Shen X. Xu X, et al. J Biol Chem. 2015 Aug 7;290(32):19888-99. doi: 10.1074/jbc.M114.630475. Epub 2015 Jun 22. J Biol Chem. 2015. PMID: 26100621 Free PMC article.

5

D-Alanine:D-alanine ligase as a new target for the flavonoids quercetin and apigenin.

Wu D, Kong Y, Han C, Chen J, Hu L, Jiang H, Shen X. Wu D, et al. Among authors: hu l. Int J Antimicrob Agents. 2008 Nov;32(5):421-6. doi: 10.1016/j.ijantimicag.2008.06.010. Epub 2008 Sep 5. Int J Antimicrob Agents. 2008. PMID: 18774266

6

Oleanolic acid derivative NPLC441 potently stimulates glucose transport in 3T3-L1 adipocytes via a multi-target mechanism.

Lin Z, Zhang Y, Zhang Y, Shen H, Hu L, Jiang H, Shen X. Lin Z, et al. Among authors: hu l. Biochem Pharmacol. 2008 Nov 15;76(10):1251-62. doi: 10.1016/j.bcp.2008.08.016. Epub 2008 Aug 22. Biochem Pharmacol. 2008. PMID: 18778688

7

Three flavonoids targeting the beta-hydroxyacyl-acyl carrier protein dehydratase from Helicobacter pylori: crystal structure characterization with enzymatic inhibition assay.

Zhang L, Kong Y, Wu D, Zhang H, Wu J, Chen J, Ding J, Hu L, Jiang H, Shen X. Zhang L, et al. Among authors: hu l. Protein Sci. 2008 Nov;17(11):1971-8. doi: 10.1110/ps.036186.108. Epub 2008 Sep 9. Protein Sci. 2008. PMID: 18780820 Free PMC article.

8

Danshen extract 15,16-dihydrotanshinone I functions as a potential modulator against metabolic syndrome through multi-target pathways.

Liu Q, Zhang Y, Lin Z, Shen H, Chen L, Hu L, Jiang H, Shen X. Liu Q, et al. Among authors: hu l. J Steroid Biochem Mol Biol. 2010 Jun;120(4-5):155-63. doi: 10.1016/j.jsbmb.2010.03.090. Epub 2010 Apr 7. J Steroid Biochem Mol Biol. 2010. PMID: 20380878

9

2,2',4'-trihydroxychalcone from Glycyrrhiza glabra as a new specific BACE1 inhibitor efficiently ameliorates memory impairment in mice.

Zhu Z, Li C, Wang X, Yang Z, Chen J, Hu L, Jiang H, Shen X. Zhu Z, et al. Among authors: hu l. J Neurochem. 2010 Jul;114(2):374-85. doi: 10.1111/j.1471-4159.2010.06751.x. Epub 2010 Apr 19. J Neurochem. 2010. PMID: 20412384 Free article.

10

Small molecules from natural sources, targeting signaling pathways in diabetes.

Liu Q, Chen L, Hu L, Guo Y, Shen X. Liu Q, et al. Among authors: hu l. Biochim Biophys Acta. 2010 Oct-Dec;1799(10-12):854-65. doi: 10.1016/j.bbagrm.2010.06.004. Epub 2010 Jun 23. Biochim Biophys Acta. 2010. PMID: 20601278 Review.

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