Dougall WC - Search Results

1

Combined inhibition of the BMP pathway and the RANK-RANKL axis in a mixed lytic/blastic prostate cancer lesion.

Virk MS, Alaee F, Petrigliano FA, Sugiyama O, Chatziioannou AF, Stout D, Dougall WC, Lieberman JR. Virk MS, et al. Among authors: dougall wc. Bone. 2011 Mar 1;48(3):578-87. doi: 10.1016/j.bone.2010.11.003. Epub 2010 Nov 10. Bone. 2011. PMID: 21073986 Free PMC article.

2

The effects of RANK blockade and osteoclast depletion in a model of pure osteoblastic prostate cancer metastasis in bone.

Whang PG, Schwarz EM, Gamradt SC, Dougall WC, Lieberman JR. Whang PG, et al. Among authors: dougall wc. J Orthop Res. 2005 Nov;23(6):1475-83. doi: 10.1016/j.orthres.2005.05.004.1100230634. Epub 2005 Jul 6. J Orthop Res. 2005. PMID: 16005175 Free article.

3

Mixed metastatic lung cancer lesions in bone are inhibited by noggin overexpression and Rank:Fc administration.

Feeley BT, Liu NQ, Conduah AH, Krenek L, Roth K, Dougall WC, Huard J, Dubinett S, Lieberman JR. Feeley BT, et al. Among authors: dougall wc. J Bone Miner Res. 2006 Oct;21(10):1571-80. doi: 10.1359/jbmr.060706. J Bone Miner Res. 2006. PMID: 16995812 Free article.

4

Influence of simultaneous targeting of the bone morphogenetic protein pathway and RANK/RANKL axis in osteolytic prostate cancer lesion in bone.

Virk MS, Petrigliano FA, Liu NQ, Chatziioannou AF, Stout D, Kang CO, Dougall WC, Lieberman JR. Virk MS, et al. Among authors: dougall wc. Bone. 2009 Jan;44(1):160-7. doi: 10.1016/j.bone.2008.09.009. Epub 2008 Sep 26. Bone. 2009. PMID: 18929692 Free PMC article.

5

Inhibition of RANKL increases the anti-tumor effect of the EGFR inhibitor panitumumab in a murine model of bone metastasis.

Canon J, Bryant R, Roudier M, Osgood T, Jones J, Miller R, Coxon A, Radinsky R, Dougall WC. Canon J, et al. Among authors: dougall wc. Bone. 2010 Jun;46(6):1613-9. doi: 10.1016/j.bone.2010.03.001. Epub 2010 Mar 6. Bone. 2010. PMID: 20215062

6

In vivo RANK signaling blockade using the receptor activator of NF-kappaB:Fc effectively prevents and ameliorates wear debris-induced osteolysis via osteoclast depletion without inhibiting osteogenesis.

Childs LM, Paschalis EP, Xing L, Dougall WC, Anderson D, Boskey AL, Puzas JE, Rosier RN, O'Keefe RJ, Boyce BF, Schwarz EM. Childs LM, et al. Among authors: dougall wc. J Bone Miner Res. 2002 Feb;17(2):192-9. doi: 10.1359/jbmr.2002.17.2.192. J Bone Miner Res. 2002. PMID: 11811549 Free article.

7

The RANK/RANKL/OPG triad in cancer-induced bone diseases.

Dougall WC, Chaisson M. Dougall WC, et al. Cancer Metastasis Rev. 2006 Dec;25(4):541-9. doi: 10.1007/s10555-006-9021-3. Cancer Metastasis Rev. 2006. PMID: 17180711 Review.

8

RANKL acts directly on RANK-expressing prostate tumor cells and mediates migration and expression of tumor metastasis genes.

Armstrong AP, Miller RE, Jones JC, Zhang J, Keller ET, Dougall WC. Armstrong AP, et al. Among authors: dougall wc. Prostate. 2008 Jan 1;68(1):92-104. doi: 10.1002/pros.20678. Prostate. 2008. PMID: 18008334 Free article.

9

RANKL inhibition is an effective adjuvant for docetaxel in a prostate cancer bone metastases model.

Ignatoski KM, Escara-Wilke JF, Dai JL, Lui A, Dougall W, Daignault S, Yao Z, Zhang J, Day ML, Sargent EE, Keller ET. Ignatoski KM, et al. Prostate. 2008 Jun 1;68(8):820-9. doi: 10.1002/pros.20744. Prostate. 2008. PMID: 18324676 Free PMC article.

10

RANK ligand inhibition plus docetaxel improves survival and reduces tumor burden in a murine model of prostate cancer bone metastasis.

Miller RE, Roudier M, Jones J, Armstrong A, Canon J, Dougall WC. Miller RE, et al. Among authors: dougall wc. Mol Cancer Ther. 2008 Jul;7(7):2160-9. doi: 10.1158/1535-7163.MCT-08-0046. Epub 2008 Jul 7. Mol Cancer Ther. 2008. PMID: 18606716

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