González-Bulnes P - Search Results

1

2-aminohydroxamic acid derivatives as inhibitors of Bacillus cereus phosphatidylcholine preferred phospholipase C PC-PLC(Bc).

González-Bulnes P, González-Roura A, Canals D, Delgado A, Casas J, Llebaria A. González-Bulnes P, et al. Bioorg Med Chem. 2010 Dec 15;18(24):8549-55. doi: 10.1016/j.bmc.2010.10.031. Epub 2010 Oct 20. Bioorg Med Chem. 2010. PMID: 21071231

2

Potent aminocyclitol glucocerebrosidase inhibitors are subnanomolar pharmacological chaperones for treating gaucher disease.

Trapero A, González-Bulnes P, Butters TD, Llebaria A. Trapero A, et al. Among authors: gonzalez bulnes p. J Med Chem. 2012 May 10;55(9):4479-88. doi: 10.1021/jm300342q. Epub 2012 May 1. J Med Chem. 2012. PMID: 22512696

3

Practical synthesis of (-)-1-amino-1-deoxy-myo-inositol from achiral precursors.

Gonzalez-Bulnes P, Casas J, Delgado A, Llebaria A. Gonzalez-Bulnes P, et al. Carbohydr Res. 2007 Sep 3;342(12-13):1947-52. doi: 10.1016/j.carres.2007.04.024. Epub 2007 May 5. Carbohydr Res. 2007. PMID: 17524374

4

PG12, a phospholipid analog with potent antimalarial activity, inhibits Plasmodium falciparum CTP:phosphocholine cytidylyltransferase activity.

González-Bulnes P, Bobenchik AM, Augagneur Y, Cerdan R, Vial HJ, Llebaria A, Ben Mamoun C. González-Bulnes P, et al. J Biol Chem. 2011 Aug 19;286(33):28940-28947. doi: 10.1074/jbc.M111.268946. Epub 2011 Jun 25. J Biol Chem. 2011. PMID: 21705805 Free PMC article.

5

Integrated synthetic, pharmacological, and computational investigation of cis-2-(3,5-dichlorophenylcarbamoyl)cyclohexanecarboxylic acid enantiomers as positive allosteric modulators of metabotropic glutamate receptor subtype 4.

Christov C, González-Bulnes P, Malhaire F, Karabencheva T, Goudet C, Pin JP, Llebaria A, Giraldo J. Christov C, et al. Among authors: gonzalez bulnes p. ChemMedChem. 2011 Jan 3;6(1):131-40. doi: 10.1002/cmdc.201000378. ChemMedChem. 2011. PMID: 21132834

6

Exploring the active conformation of cyclohexane carboxylate positive allosteric modulators of the type 4 metabotropic glutamate receptor.

Rovira X, Harrak Y, Trapero A, González-Bulnes P, Malhaire F, Pin JP, Goudet C, Giraldo J, Llebaria A. Rovira X, et al. Among authors: gonzalez bulnes p. ChemMedChem. 2014 Dec;9(12):2685-98. doi: 10.1002/cmdc.201402190. Epub 2014 Sep 5. ChemMedChem. 2014. PMID: 25196639

7

Overlapping binding sites drive allosteric agonism and positive cooperativity in type 4 metabotropic glutamate receptors.

Rovira X, Malhaire F, Scholler P, Rodrigo J, Gonzalez-Bulnes P, Llebaria A, Pin JP, Giraldo J, Goudet C. Rovira X, et al. Among authors: gonzalez bulnes p. FASEB J. 2015 Jan;29(1):116-30. doi: 10.1096/fj.14-257287. Epub 2014 Oct 23. FASEB J. 2015. PMID: 25342125

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