Chahrour M - Search Results

1

Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes.

Chao HT, Chen H, Samaco RC, Xue M, Chahrour M, Yoo J, Neul JL, Gong S, Lu HC, Heintz N, Ekker M, Rubenstein JL, Noebels JL, Rosenmund C, Zoghbi HY. Chao HT, et al. Among authors: chahrour m. Nature. 2010 Nov 11;468(7321):263-9. doi: 10.1038/nature09582. Nature. 2010. PMID: 21068835 Free PMC article.

2

The story of Rett syndrome: from clinic to neurobiology.

Chahrour M, Zoghbi HY. Chahrour M, et al. Neuron. 2007 Nov 8;56(3):422-37. doi: 10.1016/j.neuron.2007.10.001. Neuron. 2007. PMID: 17988628 Free article. Review.

3

MeCP2, a key contributor to neurological disease, activates and represses transcription.

Chahrour M, Jung SY, Shaw C, Zhou X, Wong ST, Qin J, Zoghbi HY. Chahrour M, et al. Science. 2008 May 30;320(5880):1224-9. doi: 10.1126/science.1153252. Science. 2008. PMID: 18511691 Free PMC article.

4

Mouse models of MeCP2 disorders share gene expression changes in the cerebellum and hypothalamus.

Ben-Shachar S, Chahrour M, Thaller C, Shaw CA, Zoghbi HY. Ben-Shachar S, et al. Among authors: chahrour m. Hum Mol Genet. 2009 Jul 1;18(13):2431-42. doi: 10.1093/hmg/ddp181. Epub 2009 Apr 15. Hum Mol Genet. 2009. PMID: 19369296 Free PMC article.

5

Rett-causing mutations reveal two domains critical for MeCP2 function and for toxicity in MECP2 duplication syndrome mice.

Heckman LD, Chahrour MH, Zoghbi HY. Heckman LD, et al. Elife. 2014 Jun 26;3:e02676. doi: 10.7554/eLife.02676. Elife. 2014. PMID: 24970834 Free PMC article.

6

MeCP2 and histone deacetylases 1 and 2 in dorsal striatum collectively suppress repetitive behaviors.

Mahgoub M, Adachi M, Suzuki K, Liu X, Kavalali ET, Chahrour MH, Monteggia LM. Mahgoub M, et al. Among authors: chahrour mh. Nat Neurosci. 2016 Nov;19(11):1506-1512. doi: 10.1038/nn.4395. Epub 2016 Sep 26. Nat Neurosci. 2016. PMID: 27668390 Free PMC article.

7

Current Perspectives in Autism Spectrum Disorder: From Genes to Therapy.

Chahrour M, O'Roak BJ, Santini E, Samaco RC, Kleiman RJ, Manzini MC. Chahrour M, et al. J Neurosci. 2016 Nov 9;36(45):11402-11410. doi: 10.1523/JNEUROSCI.2335-16.2016. J Neurosci. 2016. PMID: 27911742 Free PMC article. Review.

8

Disruption of the ATXN1-CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans.

Lu HC, Tan Q, Rousseaux MW, Wang W, Kim JY, Richman R, Wan YW, Yeh SY, Patel JM, Liu X, Lin T, Lee Y, Fryer JD, Han J, Chahrour M, Finnell RH, Lei Y, Zurita-Jimenez ME, Ahimaz P, Anyane-Yeboa K, Van Maldergem L, Lehalle D, Jean-Marcais N, Mosca-Boidron AL, Thevenon J, Cousin MA, Bro DE, Lanpher BC, Klee EW, Alexander N, Bainbridge MN, Orr HT, Sillitoe RV, Ljungberg MC, Liu Z, Schaaf CP, Zoghbi HY. Lu HC, et al. Among authors: chahrour m. Nat Genet. 2017 Apr;49(4):527-536. doi: 10.1038/ng.3808. Epub 2017 Mar 13. Nat Genet. 2017. PMID: 28288114 Free PMC article.

9

Evolution of Osteocrin as an activity-regulated factor in the primate brain.

Ataman B, Boulting GL, Harmin DA, Yang MG, Baker-Salisbury M, Yap EL, Malik AN, Mei K, Rubin AA, Spiegel I, Durresi E, Sharma N, Hu LS, Pletikos M, Griffith EC, Partlow JN, Stevens CR, Adli M, Chahrour M, Sestan N, Walsh CA, Berezovskii VK, Livingstone MS, Greenberg ME. Ataman B, et al. Among authors: chahrour m. Nature. 2016 Nov 10;539(7628):242-247. doi: 10.1038/nature20111. Nature. 2016. PMID: 27830782 Free PMC article.

10

Translating genetic and preclinical findings into autism therapies.

Chahrour M, Kleiman RJ, Manzini MC. Chahrour M, et al. Dialogues Clin Neurosci. 2017 Dec;19(4):335-343. doi: 10.31887/DCNS.2017.19.4/cmanzini. Dialogues Clin Neurosci. 2017. PMID: 29398929 Free PMC article. Review.

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