Borchelt DR - Search Results

1

Analysis of chaperone mRNA expression in the adult mouse brain by meta analysis of the Allen Brain Atlas.

Tebbenkamp AT, Borchelt DR. Tebbenkamp AT, et al. Among authors: borchelt dr. PLoS One. 2010 Oct 28;5(10):e13675. doi: 10.1371/journal.pone.0013675. PLoS One. 2010. PMID: 21060842 Free PMC article.

2

Characterization of huntingtin pathologic fragments in human Huntington disease, transgenic mice, and cell models.

Schilling G, Klevytska A, Tebbenkamp AT, Juenemann K, Cooper J, Gonzales V, Slunt H, Poirer M, Ross CA, Borchelt DR. Schilling G, et al. Among authors: borchelt dr. J Neuropathol Exp Neurol. 2007 Apr;66(4):313-20. doi: 10.1097/nen.0b013e318040b2c8. J Neuropathol Exp Neurol. 2007. PMID: 17413322

3

Receptor-associated protein (RAP) plays a central role in modulating Abeta deposition in APP/PS1 transgenic mice.

Xu G, Karch C, Li N, Lin N, Fromholt D, Gonzales V, Borchelt DR. Xu G, et al. Among authors: borchelt dr. PLoS One. 2008 Sep 8;3(9):e3159. doi: 10.1371/journal.pone.0003159. PLoS One. 2008. PMID: 18776935 Free PMC article.

4

Protein aggregate characterization in models of neurodegenerative disease.

Tebbenkamp AT, Borchelt DR. Tebbenkamp AT, et al. Among authors: borchelt dr. Methods Mol Biol. 2009;566:85-91. doi: 10.1007/978-1-59745-562-6_6. Methods Mol Biol. 2009. PMID: 20058166

5

Partial depletion of CREB-binding protein reduces life expectancy in a mouse model of Huntington disease.

Klevytska AM, Tebbenkamp AT, Savonenko AV, Borchelt DR. Klevytska AM, et al. Among authors: borchelt dr. J Neuropathol Exp Neurol. 2010 Apr;69(4):396-404. doi: 10.1097/NEN.0b013e3181d6c436. J Neuropathol Exp Neurol. 2010. PMID: 20448484

6

Premature death and neurologic abnormalities in transgenic mice expressing a mutant huntingtin exon-2 fragment.

Tebbenkamp AT, Swing D, Tessarollo L, Borchelt DR. Tebbenkamp AT, et al. Among authors: borchelt dr. Hum Mol Genet. 2011 Apr 15;20(8):1633-42. doi: 10.1093/hmg/ddr040. Epub 2011 Feb 9. Hum Mol Genet. 2011. PMID: 21307087 Free PMC article.

7

Transgenic mice expressing caspase-6-derived N-terminal fragments of mutant huntingtin develop neurologic abnormalities with predominant cytoplasmic inclusion pathology composed largely of a smaller proteolytic derivative.

Tebbenkamp AT, Green C, Xu G, Denovan-Wright EM, Rising AC, Fromholt SE, Brown HH, Swing D, Mandel RJ, Tessarollo L, Borchelt DR. Tebbenkamp AT, et al. Among authors: borchelt dr. Hum Mol Genet. 2011 Jul 15;20(14):2770-82. doi: 10.1093/hmg/ddr176. Epub 2011 Apr 22. Hum Mol Genet. 2011. PMID: 21515588 Free PMC article.

8

Analysis of proteolytic processes and enzymatic activities in the generation of huntingtin n-terminal fragments in an HEK293 cell model.

Tebbenkamp AT, Crosby KW, Siemienski ZB, Brown HH, Golde TE, Borchelt DR. Tebbenkamp AT, et al. Among authors: borchelt dr. PLoS One. 2012;7(12):e50750. doi: 10.1371/journal.pone.0050750. Epub 2012 Dec 7. PLoS One. 2012. PMID: 23236391 Free PMC article.

9

Experimental mutagenesis of huntingtin to map cleavage sites: different outcomes in cell and mouse models.

Tebbenkamp AT, Xu G, Siemienski ZB, Janus C, Fromholt SE, Brown HH, Swing D, Tessarollo L, Borchelt DR. Tebbenkamp AT, et al. Among authors: borchelt dr. J Huntingtons Dis. 2014;3(1):73-86. doi: 10.3233/JHD-130087. J Huntingtons Dis. 2014. PMID: 25062766

10

Messenger RNA oxidation occurs early in disease pathogenesis and promotes motor neuron degeneration in ALS.

Chang Y, Kong Q, Shan X, Tian G, Ilieva H, Cleveland DW, Rothstein JD, Borchelt DR, Wong PC, Lin CL. Chang Y, et al. Among authors: borchelt dr. PLoS One. 2008 Aug 6;3(8):e2849. doi: 10.1371/journal.pone.0002849. PLoS One. 2008. PMID: 18682740 Free PMC article.

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