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Page 1
Epigenetic regulation of the immune system in health and disease.
Fernández-Morera JL, Calvanese V, Rodríguez-Rodero S, Menéndez-Torre E, Fraga MF. Fernández-Morera JL, et al. Among authors: fraga mf. Tissue Antigens. 2010 Dec;76(6):431-9. doi: 10.1111/j.1399-0039.2010.01587.x. Tissue Antigens. 2010. PMID: 21058938 Review.
Integration of multi-omics layers empowers precision diagnosis through unveiling pathogenic mechanisms on maple syrup urine disease.
Tejedor JR, Soriano-Sexto A, Beccari L, Castejón-Fernández N, Correcher P, Sainz-Ledo L, Alba-Linares JJ, Urdinguio RG, Ugarte M, Fernández AF, Rodríguez-Pombo P, Fraga MF, Pérez B. Tejedor JR, et al. Among authors: fraga mf. J Inherit Metab Dis. 2025 Jan;48(1):e12829. doi: 10.1002/jimd.12829. Epub 2024 Dec 10. J Inherit Metab Dis. 2025. PMID: 39659154 Free PMC article.
NG2 is a target gene of MLL-AF4 and underlies glucocorticoid resistance in MLLr B-ALL by regulating NR3C1 expression.
Lopez-Millan B, Rubio-Gayarre A, Vinyoles M, Trincado JL, Fraga MF, Fernandez-Fuentes N, Guerrero-Murillo M, Martinez A, Velasco-Hernandez T, Falgàs A, Panisello C, Valcarcel G, Sardina JL, López-Martí P, Javierre BM, Del Valle-Pérez B, García de Herreros A, Locatelli F, Pieters R, Bardini M, Cazzaniga G, Rodríguez-Manzaneque JC, Hanewald T, Marschalek R, Milne TA, Stam RW, Tejedor JR, Menendez P, Bueno C. Lopez-Millan B, et al. Among authors: fraga mf. Blood. 2024 Nov 7;144(19):2002-2017. doi: 10.1182/blood.2023022050. Blood. 2024. PMID: 39093982
A multiomic atlas of the aging hippocampus reveals molecular changes in response to environmental enrichment.
Pérez RF, Tezanos P, Peñarroya A, González-Ramón A, Urdinguio RG, Gancedo-Verdejo J, Tejedor JR, Santamarina-Ojeda P, Alba-Linares JJ, Sainz-Ledo L, Roberti A, López V, Mangas C, Moro M, Cintado Reyes E, Muela Martínez P, Rodríguez-Santamaría M, Ortea I, Iglesias-Rey R, Castilla-Silgado J, Tomás-Zapico C, Iglesias-Gutiérrez E, Fernández-García B, Sanchez-Mut JV, Trejo JL, Fernández AF, Fraga MF. Pérez RF, et al. Among authors: fraga mf. Nat Commun. 2024 Jul 16;15(1):5829. doi: 10.1038/s41467-024-49608-z. Nat Commun. 2024. PMID: 39013876 Free PMC article.
The lipopolysaccharide-TLR4 axis regulates hepatic glutaminase 1 expression promoting liver ammonia build-up as steatotic liver disease progresses to steatohepatitis.
Mercado-Gómez M, Goikoetxea-Usandizaga N, Kerbert AJC, Gracianteparaluceta LU, Serrano-Maciá M, Lachiondo-Ortega S, Rodriguez-Agudo R, Gil-Pitarch C, Simón J, González-Recio I, Fondevila MF, Santamarina-Ojeda P, Fraga MF, Nogueiras R, Heras JL, Jalan R, Martínez-Chantar ML, Delgado TC. Mercado-Gómez M, et al. Among authors: fraga mf. Metabolism. 2024 Sep;158:155952. doi: 10.1016/j.metabol.2024.155952. Epub 2024 Jun 19. Metabolism. 2024. PMID: 38906371 Free article.
PCDHGC3 hypermethylation as a potential biomarker of intestinal neuroendocrine carcinomas.
Cubiella T, Celada L, San-Juan-Guardado J, Rodríguez-Aguilar R, Suárez-Priede Á, Poch M, Dominguez F, Fernández-Vega I, Montero-Pavón P, Fraga MF, Nakatani Y, Takata S, Yachida S, Valdés N, Chiara MD. Cubiella T, et al. Among authors: fraga mf. J Pathol. 2024 Aug;263(4-5):418-428. doi: 10.1002/path.6291. Epub 2024 May 25. J Pathol. 2024. PMID: 38795318
255 results