Murayama N - Search Results

1

Structure-function relationships of inhibition of human cytochromes P450 1A1, 1A2, 1B1, 2C9, and 3A4 by 33 flavonoid derivatives.

Shimada T, Tanaka K, Takenaka S, Murayama N, Martin MV, Foroozesh MK, Yamazaki H, Guengerich FP, Komori M. Shimada T, et al. Among authors: murayama n. Chem Res Toxicol. 2010 Dec 20;23(12):1921-35. doi: 10.1021/tx100286d. Chem Res Toxicol. 2010. PMID: 21053930 Free PMC article.

2

Rat cytochrome P450 2C11 in liver microsomes involved in oxidation of anesthetic agent propofol and deactivated by prior treatment with propofol.

Yamazaki H, Shimizu M, Nagashima T, Minoshima M, Murayama N. Yamazaki H, et al. Among authors: murayama n. Drug Metab Dispos. 2006 Nov;34(11):1803-5. doi: 10.1124/dmd.106.011627. Epub 2006 Aug 8. Drug Metab Dispos. 2006. PMID: 16896062

3

Different mechanisms for inhibition of human cytochromes P450 1A1, 1A2, and 1B1 by polycyclic aromatic inhibitors.

Shimada T, Murayama N, Okada K, Funae Y, Yamazaki H, Guengerich FP. Shimada T, et al. Among authors: murayama n. Chem Res Toxicol. 2007 Mar;20(3):489-96. doi: 10.1021/tx600299p. Epub 2007 Feb 10. Chem Res Toxicol. 2007. PMID: 17291012

4

Missense and nonsense mutations of the flavin-containing monooxygenase 3 gene in a Japanese cohort.

Shimizu M, Tomioka S, Murayama N, Yamazaki H. Shimizu M, et al. Among authors: murayama n. Drug Metab Pharmacokinet. 2007 Feb 25;22(1):61-4. doi: 10.2133/dmpk.22.61. Drug Metab Pharmacokinet. 2007. PMID: 17329912 Free article.

5

Roles of CYP3A4 and CYP2C19 in methyl hydroxylated and N-oxidized metabolite formation from voriconazole, a new anti-fungal agent, in human liver microsomes.

Murayama N, Imai N, Nakane T, Shimizu M, Yamazaki H. Murayama N, et al. Biochem Pharmacol. 2007 Jun 15;73(12):2020-6. doi: 10.1016/j.bcp.2007.03.012. Epub 2007 Mar 19. Biochem Pharmacol. 2007. PMID: 17433262

6

Involvement of human cytochrome P450 2B6 in the omega- and 4-hydroxylation of the anesthetic agent propofol.

Murayama N, Minoshima M, Shimizu M, Guengerich FP, Yamazaki H. Murayama N, et al. Xenobiotica. 2007 Jul;37(7):717-24. doi: 10.1080/00498250701449431. Xenobiotica. 2007. PMID: 17620218

7

Comparison of kinetic parameters for drug oxidation rates and substrate inhibition potential mediated by cytochrome P450 3A4 and 3A5.

Niwa T, Murayama N, Emoto C, Yamazaki H. Niwa T, et al. Among authors: murayama n. Curr Drug Metab. 2008 Jan;9(1):20-33. doi: 10.2174/138920008783331121. Curr Drug Metab. 2008. PMID: 18220568 Review.

8

Complex mechanism underlying transcriptional control of the haplotyped flavin-containing monooxygenase 3 (FMO3) gene in Japanese: different regulation between mutations in 5'-upstream distal region and common element in proximal region.

Shimizu M, Murayama N, Nagashima S, Fujieda M, Yamazaki H. Shimizu M, et al. Among authors: murayama n. Drug Metab Pharmacokinet. 2008;23(1):54-8. doi: 10.2133/dmpk.23.54. Drug Metab Pharmacokinet. 2008. PMID: 18305374 Free article.

9

Heterotropic cooperativity in oxidation mediated by cytochrome p450.

Niwa T, Murayama N, Yamazaki H. Niwa T, et al. Among authors: murayama n. Curr Drug Metab. 2008 Jun;9(5):453-62. doi: 10.2174/138920008784746364. Curr Drug Metab. 2008. PMID: 18537580 Review.

10

Increased transendothelial permeability of anti-cancer agent carboplatin with the aid of hyperbaric oxygenation.

Yamazaki H, Shimizu M, Murayama N, Tanaka K, Nion S, Cecchelli R. Yamazaki H, et al. Among authors: murayama n. Xenobiotica. 2008 Oct;38(10):1298-304. doi: 10.1080/00498250802405472. Xenobiotica. 2008. PMID: 18798124

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