Active site remodeling in tumor-relevant IDH1 mutants drives distinct kinetic features and potential resistance mechanisms.
Mealka M, Sierra NA, Matteo DA, Albekioni E, Khoury R, Mai T, Conley BM, Coleman NJ, Sabo KA, Komives EA, Bobkov AA, Cooksy AL, Silletti S, Schiffer JM, Huxford T, Sohl CD.
Mealka M, et al. Among authors: matteo da.
bioRxiv [Preprint]. 2024 Jan 23:2024.01.10.574970. doi: 10.1101/2024.01.10.574970.
bioRxiv. 2024.
PMID: 38260668
Free PMC article.
Updated.
Preprint.