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PML regulates apoptosis at endoplasmic reticulum by modulating calcium release.
Giorgi C, Ito K, Lin HK, Santangelo C, Wieckowski MR, Lebiedzinska M, Bononi A, Bonora M, Duszynski J, Bernardi R, Rizzuto R, Tacchetti C, Pinton P, Pandolfi PP. Giorgi C, et al. Among authors: tacchetti c. Science. 2010 Nov 26;330(6008):1247-51. doi: 10.1126/science.1189157. Epub 2010 Oct 28. Science. 2010. PMID: 21030605 Free PMC article.
Reticulon 3-dependent ER-PM contact sites control EGFR nonclathrin endocytosis.
Caldieri G, Barbieri E, Nappo G, Raimondi A, Bonora M, Conte A, Verhoef LGGC, Confalonieri S, Malabarba MG, Bianchi F, Cuomo A, Bonaldi T, Martini E, Mazza D, Pinton P, Tacchetti C, Polo S, Di Fiore PP, Sigismund S. Caldieri G, et al. Among authors: tacchetti c. Science. 2017 May 12;356(6338):617-624. doi: 10.1126/science.aah6152. Science. 2017. PMID: 28495747 Free PMC article.
BAP1 regulates IP3R3-mediated Ca2+ flux to mitochondria suppressing cell transformation.
Bononi A, Giorgi C, Patergnani S, Larson D, Verbruggen K, Tanji M, Pellegrini L, Signorato V, Olivetto F, Pastorino S, Nasu M, Napolitano A, Gaudino G, Morris P, Sakamoto G, Ferris LK, Danese A, Raimondi A, Tacchetti C, Kuchay S, Pass HI, Affar EB, Yang H, Pinton P, Carbone M. Bononi A, et al. Among authors: tacchetti c. Nature. 2017 Jun 22;546(7659):549-553. doi: 10.1038/nature22798. Epub 2017 Jun 14. Nature. 2017. PMID: 28614305 Free PMC article.
Pathological mitophagy disrupts mitochondrial homeostasis in Leber's hereditary optic neuropathy.
Danese A, Patergnani S, Maresca A, Peron C, Raimondi A, Caporali L, Marchi S, La Morgia C, Del Dotto V, Zanna C, Iannielli A, Segnali A, Di Meo I, Cavaliere A, Lebiedzinska-Arciszewska M, Wieckowski MR, Martinuzzi A, Moraes-Filho MN, Salomao SR, Berezovsky A, Belfort R Jr, Buser C, Ross-Cisneros FN, Sadun AA, Tacchetti C, Broccoli V, Giorgi C, Tiranti V, Carelli V, Pinton P. Danese A, et al. Among authors: tacchetti c. Cell Rep. 2022 Jul 19;40(3):111124. doi: 10.1016/j.celrep.2022.111124. Cell Rep. 2022. PMID: 35858578 Free PMC article.
High data output and automated 3D correlative light-electron microscopy method.
Vicidomini G, Gagliani MC, Canfora M, Cortese K, Frosi F, Santangelo C, Di Fiore PP, Boccacci P, Diaspro A, Tacchetti C. Vicidomini G, et al. Among authors: tacchetti c. Traffic. 2008 Nov;9(11):1828-38. doi: 10.1111/j.1600-0854.2008.00815.x. Epub 2008 Aug 9. Traffic. 2008. PMID: 18817522 Free PMC article.
PML restrains p53 activity and cellular senescence in clear cell renal cell carcinoma.
Simoni M, Menegazzi C, Fracassi C, Biffi CC, Genova F, Tenace NP, Lucianò R, Raimondi A, Tacchetti C, Brugarolas J, Mazza D, Bernardi R. Simoni M, et al. Among authors: tacchetti c. EMBO Mol Med. 2024 Jun;16(6):1324-1351. doi: 10.1038/s44321-024-00077-3. Epub 2024 May 10. EMBO Mol Med. 2024. PMID: 38730056 Free PMC article.
The life span determinant p66Shc localizes to mitochondria where it associates with mitochondrial heat shock protein 70 and regulates trans-membrane potential.
Orsini F, Migliaccio E, Moroni M, Contursi C, Raker VA, Piccini D, Martin-Padura I, Pelliccia G, Trinei M, Bono M, Puri C, Tacchetti C, Ferrini M, Mannucci R, Nicoletti I, Lanfrancone L, Giorgio M, Pelicci PG. Orsini F, et al. Among authors: tacchetti c. J Biol Chem. 2004 Jun 11;279(24):25689-95. doi: 10.1074/jbc.M401844200. Epub 2004 Apr 12. J Biol Chem. 2004. PMID: 15078873 Free article.
142 results