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G protein-coupled receptor APJ and its ligand apelin act downstream of Cripto to specify embryonic stem cells toward the cardiac lineage through extracellular signal-regulated kinase/p70S6 kinase signaling pathway.
D'Aniello C, Lonardo E, Iaconis S, Guardiola O, Liguoro AM, Liguori GL, Autiero M, Carmeliet P, Minchiotti G. D'Aniello C, et al. Among authors: minchiotti g. Circ Res. 2009 Jul 31;105(3):231-8. doi: 10.1161/CIRCRESAHA.109.201186. Epub 2009 Jul 2. Circ Res. 2009. PMID: 19574549
Cripto regulates skeletal muscle regeneration and modulates satellite cell determination by antagonizing myostatin.
Guardiola O, Lafuste P, Brunelli S, Iaconis S, Touvier T, Mourikis P, De Bock K, Lonardo E, Andolfi G, Bouché A, Liguori GL, Shen MM, Tajbakhsh S, Cossu G, Carmeliet P, Minchiotti G. Guardiola O, et al. Among authors: minchiotti g. Proc Natl Acad Sci U S A. 2012 Nov 20;109(47):E3231-40. doi: 10.1073/pnas.1204017109. Epub 2012 Nov 5. Proc Natl Acad Sci U S A. 2012. PMID: 23129614 Free PMC article.
Intracellular inactivation of thyroid hormone is a survival mechanism for muscle stem cell proliferation and lineage progression.
Dentice M, Ambrosio R, Damiano V, Sibilio A, Luongo C, Guardiola O, Yennek S, Zordan P, Minchiotti G, Colao A, Marsili A, Brunelli S, Del Vecchio L, Larsen PR, Tajbakhsh S, Salvatore D. Dentice M, et al. Among authors: minchiotti g. Cell Metab. 2014 Dec 2;20(6):1038-48. doi: 10.1016/j.cmet.2014.10.009. Epub 2014 Nov 13. Cell Metab. 2014. PMID: 25456740 Free PMC article.
A pre-existing population of ZEB2+ quiescent cells with stemness and mesenchymal features dictate chemoresistance in colorectal cancer.
Francescangeli F, Contavalli P, De Angelis ML, Careccia S, Signore M, Haas TL, Salaris F, Baiocchi M, Boe A, Giuliani A, Tcheremenskaia O, Pagliuca A, Guardiola O, Minchiotti G, Colace L, Ciardi A, D'Andrea V, La Torre F, Medema J, De Maria R, Zeuner A. Francescangeli F, et al. Among authors: minchiotti g. J Exp Clin Cancer Res. 2020 Jan 8;39(1):2. doi: 10.1186/s13046-019-1505-4. J Exp Clin Cancer Res. 2020. PMID: 31910865 Free PMC article.
82 results