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Intracellular inactivation of thyroid hormone is a survival mechanism for muscle stem cell proliferation and lineage progression.
Dentice M, Ambrosio R, Damiano V, Sibilio A, Luongo C, Guardiola O, Yennek S, Zordan P, Minchiotti G, Colao A, Marsili A, Brunelli S, Del Vecchio L, Larsen PR, Tajbakhsh S, Salvatore D. Dentice M, et al. Among authors: larsen pr. Cell Metab. 2014 Dec 2;20(6):1038-48. doi: 10.1016/j.cmet.2014.10.009. Epub 2014 Nov 13. Cell Metab. 2014. PMID: 25456740 Free PMC article.
Sonic hedgehog-induced type 3 deiodinase blocks thyroid hormone action enhancing proliferation of normal and malignant keratinocytes.
Dentice M, Luongo C, Huang S, Ambrosio R, Elefante A, Mirebeau-Prunier D, Zavacki AM, Fenzi G, Grachtchouk M, Hutchin M, Dlugosz AA, Bianco AC, Missero C, Larsen PR, Salvatore D. Dentice M, et al. Among authors: larsen pr. Proc Natl Acad Sci U S A. 2007 Sep 4;104(36):14466-71. doi: 10.1073/pnas.0706754104. Epub 2007 Aug 24. Proc Natl Acad Sci U S A. 2007. PMID: 17720805 Free PMC article.
Type 2 iodothyronine deiodinase levels are higher in slow-twitch than fast-twitch mouse skeletal muscle and are increased in hypothyroidism.
Marsili A, Ramadan W, Harney JW, Mulcahey M, Castroneves LA, Goemann IM, Wajner SM, Huang SA, Zavacki AM, Maia AL, Dentice M, Salvatore D, Silva JE, Larsen PR. Marsili A, et al. Among authors: larsen pr. Endocrinology. 2010 Dec;151(12):5952-60. doi: 10.1210/en.2010-0631. Epub 2010 Sep 29. Endocrinology. 2010. PMID: 20881246 Free PMC article.
320 results