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Intramolecular cyclization of N-phenyl N'(2-chloroethyl)ureas leads to active N-phenyl-4,5-dihydrooxazol-2-amines alkylating β-tubulin Glu198 and prohibitin Asp40.
Trzeciakiewicz A, Fortin S, Moreau E, C-Gaudreault R, Lacroix J, Chambon C, Communal Y, Chezal JM, Miot-Noirault E, Bouchon B, Degoul F. Trzeciakiewicz A, et al. Among authors: bouchon b. Biochem Pharmacol. 2011 May 1;81(9):1116-23. doi: 10.1016/j.bcp.2011.02.014. Epub 2011 Mar 1. Biochem Pharmacol. 2011. PMID: 21371445 Free article.
Alkylation of beta-tubulin on Glu 198 by a microtubule disrupter.
Bouchon B, Chambon C, Mounetou E, Papon J, Miot-Noirault E, Gaudreault RC, Madelmont JC, Degoul F. Bouchon B, et al. Mol Pharmacol. 2005 Nov;68(5):1415-22. doi: 10.1124/mol.105.015586. Epub 2005 Aug 12. Mol Pharmacol. 2005. PMID: 16099845
N-(4-iodophenyl)-N'-(2-chloroethyl)urea as a microtubule disrupter: in vitro and in vivo profiling of antitumoral activity on CT-26 murine colon carcinoma cell line cultured and grafted to mice.
Borel M, Degoul F, Communal Y, Mounetou E, Bouchon B, C-Gaudreault R, Madelmont JC, Miot-Noirault E. Borel M, et al. Among authors: bouchon b. Br J Cancer. 2007 Jun 4;96(11):1684-91. doi: 10.1038/sj.bjc.6603778. Epub 2007 May 8. Br J Cancer. 2007. PMID: 17486131 Free PMC article.
Annexin A1 in primary tumors promotes melanoma dissemination.
Boudhraa Z, Rondepierre F, Ouchchane L, Kintossou R, Trzeciakiewicz A, Franck F, Kanitakis J, Labeille B, Joubert-Zakeyh J, Bouchon B, Perrot JL, Mansard S, Papon J, Dechelotte P, Chezal JM, Miot-Noirault E, Bonnet M, D'Incan M, Degoul F. Boudhraa Z, et al. Among authors: bouchon b. Clin Exp Metastasis. 2014 Oct;31(7):749-60. doi: 10.1007/s10585-014-9665-2. Epub 2014 Jul 6. Clin Exp Metastasis. 2014. PMID: 24997993
Antibody PEGylation in bioorthogonal pretargeting with trans-cyclooctene/tetrazine cycloaddition: in vitro and in vivo evaluation in colorectal cancer models.
Rondon A, Ty N, Bequignat JB, Quintana M, Briat A, Witkowski T, Bouchon B, Boucheix C, Miot-Noirault E, Pouget JP, Chezal JM, Navarro-Teulon I, Moreau E, Degoul F. Rondon A, et al. Among authors: bouchon b. Sci Rep. 2017 Nov 2;7(1):14918. doi: 10.1038/s41598-017-15051-y. Sci Rep. 2017. PMID: 29097747 Free PMC article.
Annexin A1 localization and its relevance to cancer.
Boudhraa Z, Bouchon B, Viallard C, D'Incan M, Degoul F. Boudhraa Z, et al. Among authors: bouchon b. Clin Sci (Lond). 2016 Feb;130(4):205-20. doi: 10.1042/CS20150415. Clin Sci (Lond). 2016. PMID: 26769657 Review.
47 results