Frost P - Search Results

1

IL-6-induced enhancement of c-Myc translation in multiple myeloma cells: critical role of cytoplasmic localization of the rna-binding protein hnRNP A1.

Shi Y, Frost P, Hoang B, Benavides A, Gera J, Lichtenstein A. Shi Y, et al. Among authors: frost p. J Biol Chem. 2011 Jan 7;286(1):67-78. doi: 10.1074/jbc.M110.153221. Epub 2010 Oct 25. J Biol Chem. 2011. PMID: 20974848 Free PMC article.

2

Interleukin-6 activates phosphoinositol-3' kinase in multiple myeloma tumor cells by signaling through RAS-dependent and, separately, through p85-dependent pathways.

Hsu JH, Shi Y, Frost P, Yan H, Hoang B, Sharma S, Gera J, Lichtenstein A. Hsu JH, et al. Among authors: frost p. Oncogene. 2004 Apr 22;23(19):3368-75. doi: 10.1038/sj.onc.1207459. Oncogene. 2004. PMID: 15021914

3

In vivo antitumor effects of the mTOR inhibitor CCI-779 against human multiple myeloma cells in a xenograft model.

Frost P, Moatamed F, Hoang B, Shi Y, Gera J, Yan H, Frost P, Gibbons J, Lichtenstein A. Frost P, et al. Blood. 2004 Dec 15;104(13):4181-7. doi: 10.1182/blood-2004-03-1153. Epub 2004 Aug 10. Blood. 2004. PMID: 15304393 Free article.

4

Mammalian target of rapamycin inhibitors activate the AKT kinase in multiple myeloma cells by up-regulating the insulin-like growth factor receptor/insulin receptor substrate-1/phosphatidylinositol 3-kinase cascade.

Shi Y, Yan H, Frost P, Gera J, Lichtenstein A. Shi Y, et al. Among authors: frost p. Mol Cancer Ther. 2005 Oct;4(10):1533-40. doi: 10.1158/1535-7163.MCT-05-0068. Mol Cancer Ther. 2005. PMID: 16227402

5

Mechanism by which mammalian target of rapamycin inhibitors sensitize multiple myeloma cells to dexamethasone-induced apoptosis.

Yan H, Frost P, Shi Y, Hoang B, Sharma S, Fisher M, Gera J, Lichtenstein A. Yan H, et al. Among authors: frost p. Cancer Res. 2006 Feb 15;66(4):2305-13. doi: 10.1158/0008-5472.CAN-05-2447. Cancer Res. 2006. PMID: 16489035

6

Oncogenic RAS mutations in myeloma cells selectively induce cox-2 expression, which participates in enhanced adhesion to fibronectin and chemoresistance.

Hoang B, Zhu L, Shi Y, Frost P, Yan H, Sharma S, Sharma S, Goodglick L, Dubinett S, Lichtenstein A. Hoang B, et al. Among authors: frost p. Blood. 2006 Jun 1;107(11):4484-90. doi: 10.1182/blood-2005-09-3926. Epub 2006 Feb 23. Blood. 2006. PMID: 16497971 Free PMC article.

7

AKT activity regulates the ability of mTOR inhibitors to prevent angiogenesis and VEGF expression in multiple myeloma cells.

Frost P, Shi Y, Hoang B, Lichtenstein A. Frost P, et al. Oncogene. 2007 Apr 5;26(16):2255-62. doi: 10.1038/sj.onc.1210019. Epub 2006 Oct 2. Oncogene. 2007. PMID: 17016437

8

IL-6-induced stimulation of c-myc translation in multiple myeloma cells is mediated by myc internal ribosome entry site function and the RNA-binding protein, hnRNP A1.

Shi Y, Frost PJ, Hoang BQ, Benavides A, Sharma S, Gera JF, Lichtenstein AK. Shi Y, et al. Cancer Res. 2008 Dec 15;68(24):10215-22. doi: 10.1158/0008-5472.CAN-08-1066. Cancer Res. 2008. PMID: 19074889 Free PMC article.

9

Regulation of D-cyclin translation inhibition in myeloma cells treated with mammalian target of rapamycin inhibitors: rationale for combined treatment with extracellular signal-regulated kinase inhibitors and rapamycin.

Frost P, Shi Y, Hoang B, Gera J, Lichtenstein A. Frost P, et al. Mol Cancer Ther. 2009 Jan;8(1):83-93. doi: 10.1158/1535-7163.MCT-08-0254. Mol Cancer Ther. 2009. PMID: 19139116 Free PMC article.

10

Effect of autophagy on multiple myeloma cell viability.

Hoang B, Benavides A, Shi Y, Frost P, Lichtenstein A. Hoang B, et al. Among authors: frost p. Mol Cancer Ther. 2009 Jul;8(7):1974-84. doi: 10.1158/1535-7163.MCT-08-1177. Epub 2009 Jun 9. Mol Cancer Ther. 2009. PMID: 19509276

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