Lam Y - Search Results

1

Synthesis and biological evaluation of polyenylpyrrole derivatives as anticancer agents acting through caspases-dependent apoptosis.

Fang Z, Liao PC, Yang YL, Yang FL, Chen YL, Lam Y, Hua KF, Wu SH. Fang Z, et al. Among authors: lam y. J Med Chem. 2010 Nov 25;53(22):7967-78. doi: 10.1021/jm100619x. Epub 2010 Oct 22. J Med Chem. 2010. PMID: 20964408

2

Traceless solid-phase synthesis of nitrogen-containing heterocycles and their biological evaluations as inhibitors of neuronal sodium channels.

Kong KH, Chen Y, Ma X, Chui WK, Lam Y. Kong KH, et al. Among authors: lam y. J Comb Chem. 2004 Nov-Dec;6(6):928-33. doi: 10.1021/cc049910t. J Comb Chem. 2004. PMID: 15530120

3

Traceless solid-phase synthesis of substituted xanthines.

He R, Ching SM, Lam Y. He R, et al. Among authors: lam y. J Comb Chem. 2006 Nov-Dec;8(6):923-8. doi: 10.1021/cc060092+. J Comb Chem. 2006. PMID: 17096582

4

[3 + 2] Cycloaddition reactions in the synthesis of triazolo[4,5-b]pyridin-5-ones and pyrrolo[3,4-b]pyridin-2-ones.

Gao Y, Lam Y. Gao Y, et al. Among authors: lam y. J Comb Chem. 2008 Mar-Apr;10(2):327-32. doi: 10.1021/cc700183a. Epub 2008 Feb 9. J Comb Chem. 2008. PMID: 18260650

5

Synthesis and evaluation of sphingosine analogues as inhibitors of sphingosine kinases.

Wong L, Tan SS, Lam Y, Melendez AJ. Wong L, et al. Among authors: lam y. J Med Chem. 2009 Jun 25;52(12):3618-26. doi: 10.1021/jm900121d. J Med Chem. 2009. PMID: 19469544

6

Synthesis and disulfide bond connectivity-activity studies of a kalata B1-inspired cyclopeptide against dengue NS2B-NS3 protease.

Gao Y, Cui T, Lam Y. Gao Y, et al. Among authors: lam y. Bioorg Med Chem. 2010 Feb;18(3):1331-6. doi: 10.1016/j.bmc.2009.12.026. Epub 2009 Dec 29. Bioorg Med Chem. 2010. PMID: 20042339

7

Synthesis of cyclic di-nucleotidic acids as potential inhibitors targeting diguanylate cyclase.

Ching SM, Tan WJ, Chua KL, Lam Y. Ching SM, et al. Among authors: lam y. Bioorg Med Chem. 2010 Sep 15;18(18):6657-65. doi: 10.1016/j.bmc.2010.07.068. Epub 2010 Aug 4. Bioorg Med Chem. 2010. PMID: 20797869

8

Generation of reactive oxygen species by polyenylpyrroles derivatives causes DNA damage leading to G2/M arrest and apoptosis in human oral squamous cell carcinoma cells.

Hua KF, Liao PC, Fang Z, Yang FL, Yang YL, Chen YL, Chiu YC, Liu ML, Lam Y, Wu SH. Hua KF, et al. Among authors: lam y. PLoS One. 2013 Jun 28;8(6):e67603. doi: 10.1371/journal.pone.0067603. Print 2013. PLoS One. 2013. PMID: 23840748 Free PMC article.

9

Synthesis and in vitro evaluation of West Nile virus protease inhibitors based on the 1,3,4,5-tetrasubstituted 1H-pyrrol-2(5H)-one scaffold.

Gao Y, Samanta S, Cui T, Lam Y. Gao Y, et al. Among authors: lam y. ChemMedChem. 2013 Sep;8(9):1554-60. doi: 10.1002/cmdc.201300244. Epub 2013 Jul 18. ChemMedChem. 2013. PMID: 23868614

10

Polyenylpyrrole derivatives inhibit NLRP3 inflammasome activation and inflammatory mediator expression by reducing reactive oxygen species production and mitogen-activated protein kinase activation.

Hua KF, Chou JC, Lam Y, Tasi YL, Chen A, Ka SM, Fang Z, Liu ML, Yang FL, Yang YL, Chiu YC, Wu SH. Hua KF, et al. Among authors: lam y. PLoS One. 2013 Oct 7;8(10):e76754. doi: 10.1371/journal.pone.0076754. eCollection 2013. PLoS One. 2013. PMID: 24116148 Free PMC article.

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