Pérez-Ruixo JJ - Search Results

1

Pharmacodynamics-mediated drug disposition (PDMDD) and precursor pool lifespan model for single dose of romiplostim in healthy subjects.

Wang YM, Krzyzanski W, Doshi S, Xiao JJ, Pérez-Ruixo JJ, Chow AT. Wang YM, et al. AAPS J. 2010 Dec;12(4):729-40. doi: 10.1208/s12248-010-9234-9. Epub 2010 Oct 21. AAPS J. 2010. PMID: 20963535 Free PMC article.

2

Pharmacokinetics of anti-hepcidin monoclonal antibody Ab 12B9m and hepcidin in cynomolgus monkeys.

Xiao JJ, Krzyzanski W, Wang YM, Li H, Rose MJ, Ma M, Wu Y, Hinkle B, Perez-Ruixo JJ. Xiao JJ, et al. AAPS J. 2010 Dec;12(4):646-57. doi: 10.1208/s12248-010-9222-0. Epub 2010 Aug 25. AAPS J. 2010. PMID: 20737261 Free PMC article.

3

The utility of modeling and simulation approaches to evaluate immunogenicity effect on the therapeutic protein pharmacokinetics.

Perez Ruixo JJ, Ma P, Chow AT. Perez Ruixo JJ, et al. AAPS J. 2013 Jan;15(1):172-82. doi: 10.1208/s12248-012-9424-8. Epub 2012 Nov 10. AAPS J. 2013. PMID: 23139019 Free PMC article. Review.

4

Romiplostim dose-response in patients with myelodysplastic syndromes.

Perez Ruixo JJ, Doshi S, Wang YM, Mould DR. Perez Ruixo JJ, et al. Br J Clin Pharmacol. 2013 Jun;75(6):1445-54. doi: 10.1111/bcp.12041. Br J Clin Pharmacol. 2013. PMID: 23171070 Free PMC article.

5

Pharmacodynamic Model of Hepcidin Regulation of Iron Homeostasis in Cynomolgus Monkeys.

Krzyzanski W, Xiao JJ, Sasu B, Hinkle B, Perez-Ruixo JJ. Krzyzanski W, et al. AAPS J. 2016 May;18(3):713-27. doi: 10.1208/s12248-016-9886-1. Epub 2016 Feb 25. AAPS J. 2016. PMID: 26917226 Free PMC article.

6

Romiplostim dose response in patients with immune thrombocytopenia.

Perez-Ruixo JJ, Green B, Doshi S, Wang YM, Mould DR. Perez-Ruixo JJ, et al. J Clin Pharmacol. 2012 Oct;52(10):1540-51. doi: 10.1177/0091270011420843. Epub 2011 Dec 13. J Clin Pharmacol. 2012. PMID: 22167563 Clinical Trial.

7

Population pharmacokinetic meta-analysis of denosumab in healthy subjects and postmenopausal women with osteopenia or osteoporosis.

Sutjandra L, Rodriguez RD, Doshi S, Ma M, Peterson MC, Jang GR, Chow AT, Pérez-Ruixo JJ. Sutjandra L, et al. Clin Pharmacokinet. 2011 Dec 1;50(12):793-807. doi: 10.2165/11594240-000000000-00000. Clin Pharmacokinet. 2011. PMID: 22087866

8

Denosumab dose selection for patients with bone metastases from solid tumors.

Doshi S, Sutjandra L, Zheng J, Sohn W, Peterson M, Jang G, Chow AT, Pérez-Ruixo JJ. Doshi S, et al. Clin Cancer Res. 2012 May 1;18(9):2648-57. doi: 10.1158/1078-0432.CCR-11-2944. Epub 2012 Mar 6. Clin Cancer Res. 2012. PMID: 22394983

9

Pharmacokinetic and pharmacodynamic modeling of romiplostim in animals.

Krzyzanski W, Sutjandra L, Perez-Ruixo JJ, Sloey B, Chow AT, Wang YM. Krzyzanski W, et al. Pharm Res. 2013 Mar;30(3):655-69. doi: 10.1007/s11095-012-0894-2. Epub 2012 Dec 19. Pharm Res. 2013. PMID: 23250851

10

Clinical pharmacokinetics and pharmacodynamics of erythropoiesis-stimulating agents.

Doshi S, Krzyzanski W, Yue S, Elliott S, Chow A, Pérez-Ruixo JJ. Doshi S, et al. Clin Pharmacokinet. 2013 Dec;52(12):1063-83. doi: 10.1007/s40262-013-0098-x. Clin Pharmacokinet. 2013. PMID: 23912564 Review.

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