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Page 1
Evaluation of benzo(a)pyrene-induced gene mutations in male germ cells.
Verhofstad N, van Oostrom CT, Zwart E, Maas LM, van Benthem J, van Schooten FJ, van Steeg H, Godschalk RW. Verhofstad N, et al. Among authors: van steeg h, van schooten fj, van benthem j, van oostrom ct. Toxicol Sci. 2011 Jan;119(1):218-23. doi: 10.1093/toxsci/kfq325. Epub 2010 Oct 20. Toxicol Sci. 2011. PMID: 20961952
p53 heterozygosity results in an increased 2-acetylaminofluorene-induced urinary bladder but not liver tumor response in DNA repair-deficient Xpa mice.
Hoogervorst EM, van Oostrom CT, Beems RB, van Benthem J, Gielis S, Vermeulen JP, Wester PW, Vos JG, de Vries A, van Steeg H. Hoogervorst EM, et al. Among authors: van steeg h, van benthem j, van oostrom ct. Cancer Res. 2004 Aug 1;64(15):5118-26. doi: 10.1158/0008-5472.CAN-04-0350. Cancer Res. 2004. PMID: 15289314
2-AAF-induced tumor development in nucleotide excision repair-deficient mice is associated with a defect in global genome repair but not with transcription coupled repair.
Hoogervorst EM, van Oostrom CT, Beems RB, van Benthem J, van den Berg J, van Kreijl CF, Vos JG, de Vries A, van Steeg H. Hoogervorst EM, et al. Among authors: van den berg j, van kreijl cf, van steeg h, van benthem j, van oostrom ct. DNA Repair (Amst). 2005 Jan 2;4(1):3-9. doi: 10.1016/j.dnarep.2004.08.009. DNA Repair (Amst). 2005. PMID: 15533832
Identifying germ cell mutagens using OECD test guideline 488 (transgenic rodent somatic and germ cell gene mutation assays) and integration with somatic cell testing.
Marchetti F, Aardema MJ, Beevers C, van Benthem J, Godschalk R, Williams A, Yauk CL, Young R, Douglas GR. Marchetti F, et al. Among authors: van benthem j. Mutat Res Genet Toxicol Environ Mutagen. 2018 Aug;832-833:7-18. doi: 10.1016/j.mrgentox.2018.05.021. Epub 2018 May 29. Mutat Res Genet Toxicol Environ Mutagen. 2018. PMID: 30057023 Free article.
lacZ mouse embryonic fibroblasts detect both clastogens and mutagens.
Mahabir AG, Zwart E, Schaap M, van Benthem J, de Vries A, Hernandez LG, Hendriksen CF, van Steeg H. Mahabir AG, et al. Among authors: van steeg h, van benthem j. Mutat Res. 2009 Jun 18;666(1-2):50-6. doi: 10.1016/j.mrfmmm.2009.04.005. Epub 2009 Apr 23. Mutat Res. 2009. PMID: 19393670
Is MutaMouse insensitive to clastogens?
Lynch AM, Mahabir AG, Bradford A, Brockhurst K, van Benthem J, van Steeg H, Rees RW. Lynch AM, et al. Among authors: van steeg h, van benthem j. Mutat Res. 2008 Apr 30;652(2):145-50. doi: 10.1016/j.mrgentox.2008.01.008. Epub 2008 Feb 23. Mutat Res. 2008. PMID: 18387845
109 results