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Design and synthesis of tetrahydropyridothieno[2,3-d]pyrimidine scaffold based epidermal growth factor receptor (EGFR) kinase inhibitors: the role of side chain chirality and Michael acceptor group for maximal potency.
Wu CH, Coumar MS, Chu CY, Lin WH, Chen YR, Chen CT, Shiao HY, Rafi S, Wang SY, Hsu H, Chen CH, Chang CY, Chang TY, Lien TW, Fang MY, Yeh KC, Chen CP, Yeh TK, Hsieh SH, Hsu JT, Liao CC, Chao YS, Hsieh HP. Wu CH, et al. Among authors: yeh tk, yeh kc. J Med Chem. 2010 Oct 28;53(20):7316-26. doi: 10.1021/jm100607r. J Med Chem. 2010. PMID: 20961149
Development and validation of a liquid chromatography-tandem mass spectrometry for the determination of BPR0L075, a novel antimicrotuble agent, in rat plasma: application to a pharmacokinetic study.
Chang YW, Chen WC, Lin KT, Chang L, Yao HT, Hsieh HP, Lan SJ, Chen CT, Chao YS, Yeh TK. Chang YW, et al. Among authors: yeh tk. J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Feb 1;846(1-2):162-8. doi: 10.1016/j.jchromb.2006.08.040. Epub 2006 Sep 26. J Chromatogr B Analyt Technol Biomed Life Sci. 2007. PMID: 17005456
Quantitative determination of salidroside in rat plasma by on-line solid-phase extraction integrated with high-performance liquid chromatography/electrospray ionization tandem mass spectrometry.
Chang YW, Yao HT, Hsieh SH, Lu TJ, Yeh TK. Chang YW, et al. Among authors: yeh tk. J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Sep 15;857(1):164-9. doi: 10.1016/j.jchromb.2007.06.029. Epub 2007 Jul 1. J Chromatogr B Analyt Technol Biomed Life Sci. 2007. PMID: 17631426
Novel trans-2-aryl-cyclopropylamine analogues as potent and selective dipeptidyl peptidase IV inhibitors.
Tsai TY, Hsu T, Chen CT, Cheng JH, Yeh TK, Chen X, Huang CY, Chang CN, Yeh KC, Hsieh SH, Chien CH, Chang YW, Huang CH, Huang YW, Huang CL, Wu SH, Wang MH, Lu CT, Chao YS, Jiaang WT. Tsai TY, et al. Among authors: yeh tk, yeh kc. Bioorg Med Chem. 2009 Mar 15;17(6):2388-99. doi: 10.1016/j.bmc.2009.02.020. Epub 2009 Feb 20. Bioorg Med Chem. 2009. PMID: 19261480
166 results