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K-ras mutation targeted to gastric tissue progenitor cells results in chronic inflammation, an altered microenvironment, and progression to intraepithelial neoplasia.
Okumura T, Ericksen RE, Takaishi S, Wang SS, Dubeykovskiy Z, Shibata W, Betz KS, Muthupalani S, Rogers AB, Fox JG, Rustgi AK, Wang TC. Okumura T, et al. Among authors: betz ks. Cancer Res. 2010 Nov 1;70(21):8435-45. doi: 10.1158/0008-5472.CAN-10-1506. Epub 2010 Oct 19. Cancer Res. 2010. PMID: 20959488 Free PMC article.
In vivo analysis of mouse gastrin gene regulation in enhanced GFP-BAC transgenic mice.
Takaishi S, Shibata W, Tomita H, Jin G, Yang X, Ericksen R, Dubeykovskaya Z, Asfaha S, Quante M, Betz KS, Shulkes A, Wang TC. Takaishi S, et al. Among authors: betz ks. Am J Physiol Gastrointest Liver Physiol. 2011 Feb;300(2):G334-44. doi: 10.1152/ajpgi.00134.2010. Epub 2010 Nov 4. Am J Physiol Gastrointest Liver Physiol. 2011. PMID: 21051525 Free PMC article.
Inhibition of gastric carcinogenesis by the hormone gastrin is mediated by suppression of TFF1 epigenetic silencing.
Tomita H, Takaishi S, Menheniott TR, Yang X, Shibata W, Jin G, Betz KS, Kawakami K, Minamoto T, Tomasetto C, Rio MC, Lerkowit N, Varro A, Giraud AS, Wang TC. Tomita H, et al. Among authors: betz ks. Gastroenterology. 2011 Mar;140(3):879-91. doi: 10.1053/j.gastro.2010.11.037. Epub 2010 Nov 25. Gastroenterology. 2011. PMID: 21111741 Free PMC article.
Gastrin-induced apoptosis contributes to carcinogenesis in the stomach.
Cui G, Takaishi S, Ai W, Betz KS, Florholmen J, Koh TJ, Houghton J, Pritchard DM, Wang TC. Cui G, et al. Among authors: betz ks. Lab Invest. 2006 Oct;86(10):1037-51. doi: 10.1038/labinvest.3700462. Epub 2006 Aug 7. Lab Invest. 2006. PMID: 16894354 Free article.
13 results