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Polyoxometalates functionalized by bisphosphonate ligands: synthesis, structural, magnetic, and spectroscopic characterizations and activity on tumor cell lines.
El Moll H, Zhu W, Oldfield E, Rodriguez-Albelo LM, Mialane P, Marrot J, Vila N, Mbomekallé IM, Rivière E, Duboc C, Dolbecq A. El Moll H, et al. Among authors: oldfield e. Inorg Chem. 2012 Jul 16;51(14):7921-31. doi: 10.1021/ic3010079. Epub 2012 Jun 22. Inorg Chem. 2012. PMID: 22725619 Free PMC article.
Lipophilic analogs of zoledronate and risedronate inhibit Plasmodium geranylgeranyl diphosphate synthase (GGPPS) and exhibit potent antimalarial activity.
No JH, de Macedo Dossin F, Zhang Y, Liu YL, Zhu W, Feng X, Yoo JA, Lee E, Wang K, Hui R, Freitas-Junior LH, Oldfield E. No JH, et al. Among authors: oldfield e. Proc Natl Acad Sci U S A. 2012 Mar 13;109(11):4058-63. doi: 10.1073/pnas.1118215109. Epub 2012 Mar 5. Proc Natl Acad Sci U S A. 2012. PMID: 22392982 Free PMC article.
Head-to-head prenyl tranferases: anti-infective drug targets.
Lin FY, Liu YL, Li K, Cao R, Zhu W, Axelson J, Pang R, Oldfield E. Lin FY, et al. Among authors: oldfield e. J Med Chem. 2012 May 10;55(9):4367-72. doi: 10.1021/jm300208p. Epub 2012 May 1. J Med Chem. 2012. PMID: 22486710 Free PMC article.
Farnesyl diphosphate synthase inhibitors from in silico screening.
Lindert S, Zhu W, Liu YL, Pang R, Oldfield E, McCammon JA. Lindert S, et al. Among authors: oldfield e. Chem Biol Drug Des. 2013 Jun;81(6):742-8. doi: 10.1111/cbdd.12121. Chem Biol Drug Des. 2013. PMID: 23421555 Free PMC article.
Antibacterial drug leads targeting isoprenoid biosynthesis.
Zhu W, Zhang Y, Sinko W, Hensler ME, Olson J, Molohon KJ, Lindert S, Cao R, Li K, Wang K, Wang Y, Liu YL, Sankovsky A, de Oliveira CA, Mitchell DA, Nizet V, McCammon JA, Oldfield E. Zhu W, et al. Among authors: oldfield e. Proc Natl Acad Sci U S A. 2013 Jan 2;110(1):123-8. doi: 10.1073/pnas.1219899110. Epub 2012 Dec 17. Proc Natl Acad Sci U S A. 2013. PMID: 23248302 Free PMC article.
931 results