Ahmadian MR - Search Results

1

Germline KRAS mutations cause aberrant biochemical and physical properties leading to developmental disorders.

Gremer L, Merbitz-Zahradnik T, Dvorsky R, Cirstea IC, Kratz CP, Zenker M, Wittinghofer A, Ahmadian MR. Gremer L, et al. Among authors: ahmadian mr. Hum Mutat. 2011 Jan;32(1):33-43. doi: 10.1002/humu.21377. Epub 2010 Dec 9. Hum Mutat. 2011. PMID: 20949621 Free PMC article.

2

Formation of a transition-state analog of the Ras GTPase reaction by Ras-GDP, tetrafluoroaluminate, and GTPase-activating proteins.

Mittal R, Ahmadian MR, Goody RS, Wittinghofer A. Mittal R, et al. Among authors: ahmadian mr. Science. 1996 Jul 5;273(5271):115-7. doi: 10.1126/science.273.5271.115. Science. 1996. PMID: 8658179

3

Structural differences in the minimal catalytic domains of the GTPase-activating proteins p120GAP and neurofibromin.

Ahmadian MR, Wiesmüller L, Lautwein A, Bischoff FR, Wittinghofer A. Ahmadian MR, et al. J Biol Chem. 1996 Jul 5;271(27):16409-15. doi: 10.1074/jbc.271.27.16409. J Biol Chem. 1996. PMID: 8663212 Free article.

4

Crystal structure of the GTPase-activating domain of human p120GAP and implications for the interaction with Ras.

Scheffzek K, Lautwein A, Kabsch W, Ahmadian MR, Wittinghofer A. Scheffzek K, et al. Among authors: ahmadian mr. Nature. 1996 Dec 12;384(6609):591-6. doi: 10.1038/384591a0. Nature. 1996. PMID: 8955277

5

Individual rate constants for the interaction of Ras proteins with GTPase-activating proteins determined by fluorescence spectroscopy.

Ahmadian MR, Hoffmann U, Goody RS, Wittinghofer A. Ahmadian MR, et al. Biochemistry. 1997 Apr 15;36(15):4535-41. doi: 10.1021/bi962556y. Biochemistry. 1997. PMID: 9109662

6

Aluminum fluoride associates with the small guanine nucleotide binding proteins.

Ahmadian MR, Mittal R, Hall A, Wittinghofer A. Ahmadian MR, et al. FEBS Lett. 1997 May 26;408(3):315-8. doi: 10.1016/s0014-5793(97)00422-5. FEBS Lett. 1997. PMID: 9188784 Free article.

7

The Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants.

Scheffzek K, Ahmadian MR, Kabsch W, Wiesmüller L, Lautwein A, Schmitz F, Wittinghofer A. Scheffzek K, et al. Among authors: ahmadian mr. Science. 1997 Jul 18;277(5324):333-8. doi: 10.1126/science.277.5324.333. Science. 1997. PMID: 9219684

8

The interaction of Ras with GTPase-activating proteins.

Wittinghofer A, Scheffzek K, Ahmadian MR. Wittinghofer A, et al. Among authors: ahmadian mr. FEBS Lett. 1997 Jun 23;410(1):63-7. doi: 10.1016/s0014-5793(97)00321-9. FEBS Lett. 1997. PMID: 9247124 Free article. Review.

9

Confirmation of the arginine-finger hypothesis for the GAP-stimulated GTP-hydrolysis reaction of Ras.

Ahmadian MR, Stege P, Scheffzek K, Wittinghofer A. Ahmadian MR, et al. Nat Struct Biol. 1997 Sep;4(9):686-9. doi: 10.1038/nsb0997-686. Nat Struct Biol. 1997. PMID: 9302992

10

Selective disactivation of neurofibromin GAP activity in neurofibromatosis type 1.

Klose A, Ahmadian MR, Schuelke M, Scheffzek K, Hoffmeyer S, Gewies A, Schmitz F, Kaufmann D, Peters H, Wittinghofer A, Nürnberg P. Klose A, et al. Among authors: ahmadian mr. Hum Mol Genet. 1998 Aug;7(8):1261-8. doi: 10.1093/hmg/7.8.1261. Hum Mol Genet. 1998. PMID: 9668168

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