Chalmers MJ - Search Results

1

Hydrogen/deuterium exchange reveals distinct agonist/partial agonist receptor dynamics within vitamin D receptor/retinoid X receptor heterodimer.

Zhang J, Chalmers MJ, Stayrook KR, Burris LL, Garcia-Ordonez RD, Pascal BD, Burris TP, Dodge JA, Griffin PR. Zhang J, et al. Among authors: chalmers mj. Structure. 2010 Oct 13;18(10):1332-41. doi: 10.1016/j.str.2010.07.007. Structure. 2010. PMID: 20947021 Free PMC article.

2

Probing protein ligand interactions by automated hydrogen/deuterium exchange mass spectrometry.

Chalmers MJ, Busby SA, Pascal BD, He Y, Hendrickson CL, Marshall AG, Griffin PR. Chalmers MJ, et al. Anal Chem. 2006 Feb 15;78(4):1005-14. doi: 10.1021/ac051294f. Anal Chem. 2006. PMID: 16478090

3

A two-stage differential hydrogen deuterium exchange method for the rapid characterization of protein/ligand interactions.

Chalmers MJ, Busby SA, Pascal BD, Southern MR, Griffin PR. Chalmers MJ, et al. J Biomol Tech. 2007 Sep;18(4):194-204. J Biomol Tech. 2007. PMID: 17916792 Free PMC article.

4

Partial agonists activate PPARgamma using a helix 12 independent mechanism.

Bruning JB, Chalmers MJ, Prasad S, Busby SA, Kamenecka TM, He Y, Nettles KW, Griffin PR. Bruning JB, et al. Among authors: chalmers mj. Structure. 2007 Oct;15(10):1258-71. doi: 10.1016/j.str.2007.07.014. Structure. 2007. PMID: 17937915 Free article.

5

Unique ligand binding patterns between estrogen receptor alpha and beta revealed by hydrogen-deuterium exchange.

Dai SY, Burris TP, Dodge JA, Montrose-Rafizadeh C, Wang Y, Pascal BD, Chalmers MJ, Griffin PR. Dai SY, et al. Among authors: chalmers mj. Biochemistry. 2009 Oct 13;48(40):9668-76. doi: 10.1021/bi901149t. Biochemistry. 2009. PMID: 19739677 Free PMC article.

6

Dynamics of the beta2-adrenergic G-protein coupled receptor revealed by hydrogen-deuterium exchange.

Zhang X, Chien EY, Chalmers MJ, Pascal BD, Gatchalian J, Stevens RC, Griffin PR. Zhang X, et al. Among authors: chalmers mj. Anal Chem. 2010 Feb 1;82(3):1100-8. doi: 10.1021/ac902484p. Anal Chem. 2010. PMID: 20058880 Free PMC article.

7

Differential hydrogen/deuterium exchange mass spectrometry analysis of protein-ligand interactions.

Chalmers MJ, Busby SA, Pascal BD, West GM, Griffin PR. Chalmers MJ, et al. Expert Rev Proteomics. 2011 Feb;8(1):43-59. doi: 10.1586/epr.10.109. Expert Rev Proteomics. 2011. PMID: 21329427 Free PMC article. Review.

8

DNA binding alters coactivator interaction surfaces of the intact VDR-RXR complex.

Zhang J, Chalmers MJ, Stayrook KR, Burris LL, Wang Y, Busby SA, Pascal BD, Garcia-Ordonez RD, Bruning JB, Istrate MA, Kojetin DJ, Dodge JA, Burris TP, Griffin PR. Zhang J, et al. Among authors: chalmers mj. Nat Struct Mol Biol. 2011 May;18(5):556-63. doi: 10.1038/nsmb.2046. Epub 2011 Apr 10. Nat Struct Mol Biol. 2011. PMID: 21478866 Free PMC article.

9

Methods for the Analysis of High Precision Differential Hydrogen Deuterium Exchange Data.

Chalmers MJ, Pascal BD, Willis S, Zhang J, Iturria SJ, Dodge JA, Griffin PR. Chalmers MJ, et al. Int J Mass Spectrom. 2011 Apr 30;302(1-3):59-68. doi: 10.1016/j.ijms.2010.08.002. Int J Mass Spectrom. 2011. PMID: 21528013 Free PMC article.

10

Ligand-dependent perturbation of the conformational ensemble for the GPCR β2 adrenergic receptor revealed by HDX.

West GM, Chien EY, Katritch V, Gatchalian J, Chalmers MJ, Stevens RC, Griffin PR. West GM, et al. Among authors: chalmers mj. Structure. 2011 Oct 12;19(10):1424-32. doi: 10.1016/j.str.2011.08.001. Epub 2011 Sep 1. Structure. 2011. PMID: 21889352 Free PMC article.

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