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Structures of the first representatives of Pfam family PF06938 (DUF1285) reveal a new fold with repeated structural motifs and possible involvement in signal transduction.
Han GW, Bakolitsa C, Miller MD, Kumar A, Carlton D, Najmanovich RJ, Abdubek P, Astakhova T, Axelrod HL, Chen C, Chiu HJ, Clayton T, Das D, Deller MC, Duan L, Ernst D, Feuerhelm J, Grant JC, Grzechnik A, Jaroszewski L, Jin KK, Johnson HA, Klock HE, Knuth MW, Kozbial P, Krishna SS, Marciano D, McMullan D, Morse AT, Nigoghossian E, Okach L, Reyes R, Rife CL, Sefcovic N, Tien HJ, Trame CB, van den Bedem H, Weekes D, Xu Q, Hodgson KO, Wooley J, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Wilson IA. Han GW, et al. Among authors: najmanovich rj. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Oct 1;66(Pt 10):1218-25. doi: 10.1107/S1744309109050416. Epub 2010 Mar 5. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010. PMID: 20944214 Free PMC article.
The structure of the first representative of Pfam family PF06475 reveals a new fold with possible involvement in glycolipid metabolism.
Bakolitsa C, Kumar A, McMullan D, Krishna SS, Miller MD, Carlton D, Najmanovich R, Abdubek P, Astakhova T, Chiu HJ, Clayton T, Deller MC, Duan L, Elias Y, Feuerhelm J, Grant JC, Grzechnik SK, Han GW, Jaroszewski L, Jin KK, Klock HE, Knuth MW, Kozbial P, Marciano D, Morse AT, Nigoghossian E, Okach L, Oommachen S, Paulsen J, Reyes R, Rife CL, Trout CV, van den Bedem H, Weekes D, White A, Xu Q, Hodgson KO, Wooley J, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Wilson IA. Bakolitsa C, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Oct 1;66(Pt 10):1211-7. doi: 10.1107/S1744309109022684. Epub 2009 Oct 27. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010. PMID: 20944213 Free PMC article.
Side-chain flexibility in proteins upon ligand binding.
Najmanovich R, Kuttner J, Sobolev V, Edelman M. Najmanovich R, et al. Proteins. 2000 May 15;39(3):261-8. doi: 10.1002/(sici)1097-0134(20000515)39:3<261::aid-prot90>3.0.co;2-4. Proteins. 2000. PMID: 10737948
54 results