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Modulation of gemcitabine accumulation by DNA-damaging agents: mechanisms and specificity in an in vitro model.
Anticancer Res. 2010 Sep;30(9):3669-73.
Anticancer Res. 2010.
PMID: 20944152
Randomized crossover study evaluating the effect of gemcitabine infusion dose rate: evidence of auto-induction of gemcitabine accumulation.
Grimison P, Galettis P, Manners S, Jelinek M, Metharom E, de Souza PL, Liauw W, Links MJ.
Grimison P, et al. Among authors: metharom e.
J Clin Oncol. 2007 Dec 20;25(36):5704-9. doi: 10.1200/JCO.2007.10.7078.
J Clin Oncol. 2007.
PMID: 18089865
Clinical Trial.
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The pharmacological advantage of prolonged dose rate gemcitabine is restricted to patients with variant alleles of cytidine deaminase c.79A>C.
Metharom E, Galettis P, Manners S, Jelinek M, Liauw W, de Souza PL, Hoskins JM, Links M.
Metharom E, et al.
Asia Pac J Clin Oncol. 2011 Mar;7(1):65-74. doi: 10.1111/j.1743-7563.2010.01354.x. Epub 2010 Dec 30.
Asia Pac J Clin Oncol. 2011.
PMID: 21332653
Clinical Trial.
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