Rowbotham NJ - Search Results

1

Non-redundant role for the transcription factor Gli1 at multiple stages of thymocyte development.

Drakopoulou E, Outram SV, Rowbotham NJ, Ross SE, Furmanski AL, Saldana JI, Hager-Theodorides AL, Crompton T. Drakopoulou E, et al. Among authors: rowbotham nj. Cell Cycle. 2010 Oct 15;9(20):4144-52. doi: 10.4161/cc.9.20.13453. Epub 2010 Oct 27. Cell Cycle. 2010. PMID: 20935514 Free PMC article.

2

Activation of the Hedgehog signaling pathway in T-lineage cells inhibits TCR repertoire selection in the thymus and peripheral T-cell activation.

Rowbotham NJ, Hager-Theodorides AL, Cebecauer M, Shah DK, Drakopoulou E, Dyson J, Outram SV, Crompton T. Rowbotham NJ, et al. Blood. 2007 May 1;109(9):3757-66. doi: 10.1182/blood-2006-07-037655. Epub 2007 Jan 16. Blood. 2007. PMID: 17227833 Free PMC article.

3

Beta-selection: abundance of TCRbeta-/gammadelta- CD44- CD25- (DN4) cells in the foetal thymus.

Hager-Theodorides AL, Rowbotham NJ, Outram SV, Dessens JT, Crompton T. Hager-Theodorides AL, et al. Among authors: rowbotham nj. Eur J Immunol. 2007 Feb;37(2):487-500. doi: 10.1002/eji.200636503. Eur J Immunol. 2007. PMID: 17273993 Free PMC article.

4

A novel role for Hedgehog in T-cell receptor signaling: implications for development and immunity.

Rowbotham NJ, Hager-Theodorides AL, Furmanski AL, Crompton T. Rowbotham NJ, et al. Cell Cycle. 2007 Sep 1;6(17):2138-42. doi: 10.4161/cc.6.17.4644. Epub 2007 Jun 27. Cell Cycle. 2007. PMID: 17786048 Free article.

5

Repression of hedgehog signal transduction in T-lineage cells increases TCR-induced activation and proliferation.

Rowbotham NJ, Furmanski AL, Hager-Theodorides AL, Ross SE, Drakopoulou E, Koufaris C, Outram SV, Crompton T. Rowbotham NJ, et al. Cell Cycle. 2008 Apr 1;7(7):904-8. doi: 10.4161/cc.7.7.5628. Epub 2008 Jan 18. Cell Cycle. 2008. PMID: 18414059 Free article.

6

Indian hedgehog (Ihh) both promotes and restricts thymocyte differentiation.

Outram SV, Hager-Theodorides AL, Shah DK, Rowbotham NJ, Drakopoulou E, Ross SE, Lanske B, Dessens JT, Crompton T. Outram SV, et al. Among authors: rowbotham nj. Blood. 2009 Mar 5;113(10):2217-28. doi: 10.1182/blood-2008-03-144840. Epub 2008 Dec 23. Blood. 2009. PMID: 19109233 Free article.

7

Sonic hedgehog negatively regulates pre-TCR-induced differentiation by a Gli2-dependent mechanism.

Rowbotham NJ, Hager-Theodorides AL, Furmanski AL, Ross SE, Outram SV, Dessens JT, Crompton T. Rowbotham NJ, et al. Blood. 2009 May 21;113(21):5144-56. doi: 10.1182/blood-2008-10-185751. Epub 2009 Mar 9. Blood. 2009. PMID: 19273836 Free PMC article.

8

The Gli3 transcription factor expressed in the thymus stroma controls thymocyte negative selection via Hedgehog-dependent and -independent mechanisms.

Hager-Theodorides AL, Furmanski AL, Ross SE, Outram SV, Rowbotham NJ, Crompton T. Hager-Theodorides AL, et al. Among authors: rowbotham nj. J Immunol. 2009 Sep 1;183(5):3023-32. doi: 10.4049/jimmunol.0900152. Epub 2009 Aug 10. J Immunol. 2009. PMID: 19667090

9

Role of endogenous annexin-A1 in the regulation of thymocyte positive and negative selection.

Paschalidis N, Huggins A, Rowbotham NJ, Furmanski AL, Crompton T, Flower RJ, Perretti M, D'Acquisto F. Paschalidis N, et al. Among authors: rowbotham nj. Cell Cycle. 2010 Feb 15;9(4):784-93. Epub 2010 Feb 17. Cell Cycle. 2010. PMID: 20139728

10

Role of Hedgehog signalling at the transition from double-positive to single-positive thymocyte.

Furmanski AL, Saldana JI, Rowbotham NJ, Ross SE, Crompton T. Furmanski AL, et al. Among authors: rowbotham nj. Eur J Immunol. 2012 Feb;42(2):489-99. doi: 10.1002/eji.201141758. Epub 2011 Dec 16. Eur J Immunol. 2012. PMID: 22101858 Free PMC article.

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