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Basiliolides, a class of tetracyclic C19 dilactones from Thapsia garganica, release Ca(2+) from the endoplasmic reticulum and regulate the activity of the transcription factors nuclear factor of activated T cells, nuclear factor-kappaB, and activator protein 1 in T lymphocytes.
Navarrete C, Sancho R, Caballero FJ, Pollastro F, Fiebich BL, Sterner O, Appendino G, Muñoz E. Navarrete C, et al. Among authors: appendino g. J Pharmacol Exp Ther. 2006 Oct;319(1):422-30. doi: 10.1124/jpet.106.108209. Epub 2006 Jul 13. J Pharmacol Exp Ther. 2006. PMID: 16840645
Protective role of arzanol against lipid peroxidation in biological systems.
Rosa A, Pollastro F, Atzeri A, Appendino G, Melis MP, Deiana M, Incani A, Loru D, Dessì MA. Rosa A, et al. Among authors: appendino g. Chem Phys Lipids. 2011 Jan;164(1):24-32. doi: 10.1016/j.chemphyslip.2010.09.009. Epub 2010 Oct 7. Chem Phys Lipids. 2011. PMID: 20932961
Parthenolide inhibits nociception and neurogenic vasodilatation in the trigeminovascular system by targeting the TRPA1 channel.
Materazzi S, Benemei S, Fusi C, Gualdani R, De Siena G, Vastani N, Andersson DA, Trevisan G, Moncelli MR, Wei X, Dussor G, Pollastro F, Patacchini R, Appendino G, Geppetti P, Nassini R. Materazzi S, et al. Among authors: appendino g. Pain. 2013 Dec;154(12):2750-2758. doi: 10.1016/j.pain.2013.08.002. Epub 2013 Aug 8. Pain. 2013. PMID: 23933184 Free PMC article.
Neuroactive and Anti-inflammatory Frankincense Cembranes: A Structure-Activity Study.
Pollastro F, Golin S, Chianese G, Putra MY, Schiano Moriello A, De Petrocellis L, García V, Munoz E, Taglialatela-Scafati O, Appendino G. Pollastro F, et al. Among authors: appendino g. J Nat Prod. 2016 Jul 22;79(7):1762-8. doi: 10.1021/acs.jnatprod.6b00141. Epub 2016 Jun 28. J Nat Prod. 2016. PMID: 27352042
274 results