Esser N - Search Results

1

Development of a novel prodrug of paclitaxel that is cleaved by prostate-specific antigen: an in vitro and in vivo evaluation study.

Elsadek B, Graeser R, Esser N, Schäfer-Obodozie C, Abu Ajaj K, Unger C, Warnecke A, Saleem T, El-Melegy N, Madkor H, Kratz F. Elsadek B, et al. Among authors: esser n. Eur J Cancer. 2010 Dec;46(18):3434-44. doi: 10.1016/j.ejca.2010.08.018. Eur J Cancer. 2010. PMID: 20933385

2

In vivo evaluation of a novel albumin-binding prodrug of doxorubicin in an orthotopic mouse model of prostate cancer (LNCaP).

Elsadek B, Graeser R, Esser N, Schäfer-Obodozie C, Tsurumi C, Abu Ajaj K, Warnecke A, Unger C, Saleem T, Kratz F. Elsadek B, et al. Among authors: esser n. Prostate Cancer Prostatic Dis. 2011 Mar;14(1):14-21. doi: 10.1038/pcan.2010.43. Epub 2010 Nov 2. Prostate Cancer Prostatic Dis. 2011. PMID: 21042336

3

A new approach for the treatment of malignant melanoma: enhanced antitumor efficacy of an albumin-binding doxorubicin prodrug that is cleaved by matrix metalloproteinase 2.

Mansour AM, Drevs J, Esser N, Hamada FM, Badary OA, Unger C, Fichtner I, Kratz F. Mansour AM, et al. Among authors: esser n. Cancer Res. 2003 Jul 15;63(14):4062-6. Cancer Res. 2003. PMID: 12874007

4

Synthesis and biological evaluation of an albumin-binding prodrug of doxorubicin that is cleaved by prostate-specific antigen (PSA) in a PSA-positive orthotopic prostate carcinoma model (LNCaP).

Graeser R, Chung DE, Esser N, Moor S, Schächtele C, Unger C, Kratz F. Graeser R, et al. Among authors: esser n. Int J Cancer. 2008 Mar 1;122(5):1145-54. doi: 10.1002/ijc.23050. Int J Cancer. 2008. PMID: 17973264

5

INNO-206, the (6-maleimidocaproyl hydrazone derivative of doxorubicin), shows superior antitumor efficacy compared to doxorubicin in different tumor xenograft models and in an orthotopic pancreas carcinoma model.

Graeser R, Esser N, Unger H, Fichtner I, Zhu A, Unger C, Kratz F. Graeser R, et al. Among authors: esser n. Invest New Drugs. 2010 Feb;28(1):14-9. doi: 10.1007/s10637-008-9208-2. Epub 2009 Jan 8. Invest New Drugs. 2010. PMID: 19148580

6

Probing the cysteine-34 position of endogenous serum albumin with thiol-binding doxorubicin derivatives. Improved efficacy of an acid-sensitive doxorubicin derivative with specific albumin-binding properties compared to that of the parent compound.

Kratz F, Warnecke A, Scheuermann K, Stockmar C, Schwab J, Lazar P, Drückes P, Esser N, Drevs J, Rognan D, Bissantz C, Hinderling C, Folkers G, Fichtner I, Unger C. Kratz F, et al. Among authors: esser n. J Med Chem. 2002 Dec 5;45(25):5523-33. doi: 10.1021/jm020276c. J Med Chem. 2002. PMID: 12459020

7

Liposomal gemcitabine (GemLip)-efficient drug against hormone-refractory Du145 and PC-3 prostate cancer xenografts.

Jantscheff P, Esser N, Graeser R, Ziroli V, Kluth J, Unger C, Massing U. Jantscheff P, et al. Among authors: esser n. Prostate. 2009 Aug 1;69(11):1151-63. doi: 10.1002/pros.20964. Prostate. 2009. PMID: 19399788

8

Anti-metastatic effects of liposomal gemcitabine in a human orthotopic LNCaP prostate cancer xenograft model.

Jantscheff P, Ziroli V, Esser N, Graeser R, Kluth J, Sukolinskaya A, Taylor LA, Unger C, Massing U. Jantscheff P, et al. Among authors: esser n. Clin Exp Metastasis. 2009;26(8):981-92. doi: 10.1007/s10585-009-9288-1. Epub 2009 Sep 26. Clin Exp Metastasis. 2009. PMID: 19784785

9

A new liposomal formulation of Gemcitabine is active in an orthotopic mouse model of pancreatic cancer accessible to bioluminescence imaging.

Bornmann C, Graeser R, Esser N, Ziroli V, Jantscheff P, Keck T, Unger C, Hopt UT, Adam U, Schaechtele C, Massing U, von Dobschuetz E. Bornmann C, et al. Among authors: esser n. Cancer Chemother Pharmacol. 2008 Mar;61(3):395-405. doi: 10.1007/s00280-007-0482-z. Epub 2007 Jun 7. Cancer Chemother Pharmacol. 2008. PMID: 17554540

10

Antiangiogenic potency of various chemotherapeutic drugs for metronomic chemotherapy.

Drevs J, Fakler J, Eisele S, Medinger M, Bing G, Esser N, Marmé D, Unger C. Drevs J, et al. Among authors: esser n. Anticancer Res. 2004 May-Jun;24(3a):1759-63. Anticancer Res. 2004. PMID: 15274352 Free article.

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