Tyo KE - Search Results

1

Isoprenoid pathway optimization for Taxol precursor overproduction in Escherichia coli.

Ajikumar PK, Xiao WH, Tyo KE, Wang Y, Simeon F, Leonard E, Mucha O, Phon TH, Pfeifer B, Stephanopoulos G. Ajikumar PK, et al. Among authors: tyo ke. Science. 2010 Oct 1;330(6000):70-4. doi: 10.1126/science.1191652. Science. 2010. PMID: 20929806 Free PMC article.

2

Metabolic engineering.

Raab RM, Tyo K, Stephanopoulos G. Raab RM, et al. Adv Biochem Eng Biotechnol. 2005;100:1-17. doi: 10.1007/b136411. Adv Biochem Eng Biotechnol. 2005. PMID: 16270654 Review.

3

High-throughput screen for poly-3-hydroxybutyrate in Escherichia coli and Synechocystis sp. strain PCC6803.

Tyo KE, Zhou H, Stephanopoulos GN. Tyo KE, et al. Appl Environ Microbiol. 2006 May;72(5):3412-7. doi: 10.1128/AEM.72.5.3412-3417.2006. Appl Environ Microbiol. 2006. PMID: 16672485 Free PMC article.

4

Expanding the metabolic engineering toolbox: more options to engineer cells.

Tyo KE, Alper HS, Stephanopoulos GN. Tyo KE, et al. Trends Biotechnol. 2007 Mar;25(3):132-7. doi: 10.1016/j.tibtech.2007.01.003. Epub 2007 Jan 24. Trends Biotechnol. 2007. PMID: 17254656 Review.

5

Terpenoids: opportunities for biosynthesis of natural product drugs using engineered microorganisms.

Ajikumar PK, Tyo K, Carlsen S, Mucha O, Phon TH, Stephanopoulos G. Ajikumar PK, et al. Mol Pharm. 2008 Mar-Apr;5(2):167-90. doi: 10.1021/mp700151b. Epub 2008 Mar 21. Mol Pharm. 2008. PMID: 18355030 Review.

6

A high-throughput screen for hyaluronic acid accumulation in recombinant Escherichia coli transformed by libraries of engineered sigma factors.

Yu H, Tyo K, Alper H, Klein-Marcuschamer D, Stephanopoulos G. Yu H, et al. Biotechnol Bioeng. 2008 Nov 1;101(4):788-96. doi: 10.1002/bit.21947. Biotechnol Bioeng. 2008. PMID: 18500764

7

Identification of gene disruptions for increased poly-3-hydroxybutyrate accumulation in Synechocystis PCC 6803.

Tyo KE, Jin YS, Espinoza FA, Stephanopoulos G. Tyo KE, et al. Biotechnol Prog. 2009 Sep-Oct;25(5):1236-43. doi: 10.1002/btpr.228. Biotechnol Prog. 2009. PMID: 19606467

8

Stabilized gene duplication enables long-term selection-free heterologous pathway expression.

Tyo KE, Ajikumar PK, Stephanopoulos G. Tyo KE, et al. Nat Biotechnol. 2009 Aug;27(8):760-5. doi: 10.1038/nbt.1555. Epub 2009 Jul 26. Nat Biotechnol. 2009. PMID: 19633654

9

Analysis of polyhydroxybutyrate flux limitations by systematic genetic and metabolic perturbations.

Tyo KE, Fischer CR, Simeon F, Stephanopoulos G. Tyo KE, et al. Metab Eng. 2010 May;12(3):187-95. doi: 10.1016/j.ymben.2009.10.005. Epub 2009 Oct 30. Metab Eng. 2010. PMID: 19879956

10

Directed evolution of promoters and tandem gene arrays for customizing RNA synthesis rates and regulation.

Tyo KE, Nevoigt E, Stephanopoulos G. Tyo KE, et al. Methods Enzymol. 2011;497:135-55. doi: 10.1016/B978-0-12-385075-1.00006-8. Methods Enzymol. 2011. PMID: 21601085

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