Leonard E - Search Results

1

Isoprenoid pathway optimization for Taxol precursor overproduction in Escherichia coli.

Ajikumar PK, Xiao WH, Tyo KE, Wang Y, Simeon F, Leonard E, Mucha O, Phon TH, Pfeifer B, Stephanopoulos G. Ajikumar PK, et al. Among authors: leonard e. Science. 2010 Oct 1;330(6000):70-4. doi: 10.1126/science.1191652. Science. 2010. PMID: 20929806 Free PMC article.

2

Combining metabolic and protein engineering of a terpenoid biosynthetic pathway for overproduction and selectivity control.

Leonard E, Ajikumar PK, Thayer K, Xiao WH, Mo JD, Tidor B, Stephanopoulos G, Prather KL. Leonard E, et al. Proc Natl Acad Sci U S A. 2010 Aug 3;107(31):13654-9. doi: 10.1073/pnas.1006138107. Epub 2010 Jul 19. Proc Natl Acad Sci U S A. 2010. PMID: 20643967 Free PMC article.

3

Engineering of artificial plant cytochrome P450 enzymes for synthesis of isoflavones by Escherichia coli.

Leonard E, Koffas MA. Leonard E, et al. Appl Environ Microbiol. 2007 Nov;73(22):7246-51. doi: 10.1128/AEM.01411-07. Epub 2007 Sep 28. Appl Environ Microbiol. 2007. PMID: 17905887 Free PMC article.

4

Strain improvement of recombinant Escherichia coli for efficient production of plant flavonoids.

Leonard E, Yan Y, Fowler ZL, Li Z, Lim CG, Lim KH, Koffas MA. Leonard E, et al. Mol Pharm. 2008 Mar-Apr;5(2):257-65. doi: 10.1021/mp7001472. Epub 2008 Mar 12. Mol Pharm. 2008. PMID: 18333619

5

Functional expression of a P450 flavonoid hydroxylase for the biosynthesis of plant-specific hydroxylated flavonols in Escherichia coli.

Leonard E, Yan Y, Koffas MA. Leonard E, et al. Metab Eng. 2006 Mar;8(2):172-81. doi: 10.1016/j.ymben.2005.11.001. Epub 2005 Dec 27. Metab Eng. 2006. PMID: 16384722

6

Engineering alternative butanol production platforms in heterologous bacteria.

Nielsen DR, Leonard E, Yoon SH, Tseng HC, Yuan C, Prather KL. Nielsen DR, et al. Among authors: leonard e. Metab Eng. 2009 Jul-Sep;11(4-5):262-73. doi: 10.1016/j.ymben.2009.05.003. Epub 2009 May 21. Metab Eng. 2009. PMID: 19464384 Free article.

7

Engineering central metabolic pathways for high-level flavonoid production in Escherichia coli.

Leonard E, Lim KH, Saw PN, Koffas MA. Leonard E, et al. Appl Environ Microbiol. 2007 Jun;73(12):3877-86. doi: 10.1128/AEM.00200-07. Epub 2007 Apr 27. Appl Environ Microbiol. 2007. PMID: 17468269 Free PMC article.

8

Statistics-based model for prediction of chemical biosynthesis yield from Saccharomyces cerevisiae.

Varman AM, Xiao Y, Leonard E, Tang YJ. Varman AM, et al. Among authors: leonard e. Microb Cell Fact. 2011 Jun 21;10:45. doi: 10.1186/1475-2859-10-45. Microb Cell Fact. 2011. PMID: 21689458 Free PMC article.

9

Expression of a soluble flavone synthase allows the biosynthesis of phytoestrogen derivatives in Escherichia coli.

Leonard E, Chemler J, Lim KH, Koffas MA. Leonard E, et al. Appl Microbiol Biotechnol. 2006 Mar;70(1):85-91. doi: 10.1007/s00253-005-0059-x. Epub 2005 Jul 15. Appl Microbiol Biotechnol. 2006. PMID: 16025328

10

Engineering microbes with synthetic biology frameworks.

Leonard E, Nielsen D, Solomon K, Prather KJ. Leonard E, et al. Trends Biotechnol. 2008 Dec;26(12):674-81. doi: 10.1016/j.tibtech.2008.08.003. Epub 2008 Oct 30. Trends Biotechnol. 2008. PMID: 18977048 Review.

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