Mahdi F - Search Results

1

Mammea E/BB, an isoprenylated dihydroxycoumarin protonophore that potently uncouples mitochondrial electron transport, disrupts hypoxic signaling in tumor cells.

Du L, Mahdi F, Jekabsons MB, Nagle DG, Zhou YD. Du L, et al. Among authors: mahdi f. J Nat Prod. 2010 Nov 29;73(11):1868-72. doi: 10.1021/np100501n. Epub 2010 Oct 7. J Nat Prod. 2010. PMID: 20929261 Free PMC article.

2

The Caulerpa pigment caulerpin inhibits HIF-1 activation and mitochondrial respiration.

Liu Y, Morgan JB, Coothankandaswamy V, Liu R, Jekabsons MB, Mahdi F, Nagle DG, Zhou YD. Liu Y, et al. Among authors: mahdi f. J Nat Prod. 2009 Dec;72(12):2104-9. doi: 10.1021/np9005794. J Nat Prod. 2009. PMID: 19921787 Free PMC article.

3

The alternative medicine pawpaw and its acetogenin constituents suppress tumor angiogenesis via the HIF-1/VEGF pathway.

Coothankandaswamy V, Liu Y, Mao SC, Morgan JB, Mahdi F, Jekabsons MB, Nagle DG, Zhou YD. Coothankandaswamy V, et al. Among authors: mahdi f. J Nat Prod. 2010 May 28;73(5):956-61. doi: 10.1021/np100228d. J Nat Prod. 2010. PMID: 20423107 Free PMC article.

4

The marine sponge metabolite mycothiazole: a novel prototype mitochondrial complex I inhibitor.

Morgan JB, Mahdi F, Liu Y, Coothankandaswamy V, Jekabsons MB, Johnson TA, Sashidhara KV, Crews P, Nagle DG, Zhou YD. Morgan JB, et al. Among authors: mahdi f. Bioorg Med Chem. 2010 Aug 15;18(16):5988-94. doi: 10.1016/j.bmc.2010.06.072. Epub 2010 Jun 25. Bioorg Med Chem. 2010. PMID: 20637638 Free PMC article.

5

Natural and semisynthetic mammea-type isoprenylated dihydroxycoumarins uncouple cellular respiration.

Du L, Mahdi F, Jekabsons MB, Nagle DG, Zhou YD. Du L, et al. Among authors: mahdi f. J Nat Prod. 2011 Feb 25;74(2):240-8. doi: 10.1021/np100762s. Epub 2011 Jan 7. J Nat Prod. 2011. PMID: 21214226 Free PMC article.

6

Thyrsiferol Inhibits Mitochondrial Respiration and HIF-1 Activation.

Mahdi F, Falkenberg M, Ioannou E, Roussis V, Zhou YD, Nagle DG. Mahdi F, et al. Phytochem Lett. 2011 Jun;4(2):75-78. doi: 10.1016/j.phytol.2010.09.003. Phytochem Lett. 2011. PMID: 21785662 Free PMC article.

7

Mitochondrial respiration inhibitors suppress protein translation and hypoxic signaling via the hyperphosphorylation and inactivation of translation initiation factor eIF2α and elongation factor eEF2.

Li J, Mahdi F, Du L, Datta S, Nagle DG, Zhou YD. Li J, et al. Among authors: mahdi f. J Nat Prod. 2011 Sep 23;74(9):1894-901. doi: 10.1021/np200370z. Epub 2011 Aug 29. J Nat Prod. 2011. PMID: 21875114 Free PMC article.

8

Structures and mechanisms of antitumor agents: xestoquinones uncouple cellular respiration and disrupt HIF signaling in human breast tumor cells.

Du L, Mahdi F, Datta S, Jekabsons MB, Zhou YD, Nagle DG. Du L, et al. Among authors: mahdi f. J Nat Prod. 2012 Sep 28;75(9):1553-9. doi: 10.1021/np3002892. Epub 2012 Aug 31. J Nat Prod. 2012. PMID: 22938093 Free PMC article.

9

Glycolysis inhibitor screening identifies the bis-geranylacylphloroglucinol protonophore moronone from Moronobea coccinea.

Datta S, Li J, Mahdi F, Jekabsons MB, Nagle DG, Zhou YD. Datta S, et al. Among authors: mahdi f. J Nat Prod. 2012 Dec 28;75(12):2216-22. doi: 10.1021/np300711e. Epub 2012 Dec 17. J Nat Prod. 2012. PMID: 23245650 Free PMC article.

10

Semisynthetic studies identify mitochondria poisons from botanical dietary supplements--geranyloxycoumarins from Aegle marmelos.

Li J, Mahdi F, Du L, Jekabsons MB, Zhou YD, Nagle DG. Li J, et al. Among authors: mahdi f. Bioorg Med Chem. 2013 Apr 1;21(7):1795-803. doi: 10.1016/j.bmc.2013.01.048. Epub 2013 Feb 4. Bioorg Med Chem. 2013. PMID: 23434131 Free PMC article.

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