Du L - Search Results

1

Mammea E/BB, an isoprenylated dihydroxycoumarin protonophore that potently uncouples mitochondrial electron transport, disrupts hypoxic signaling in tumor cells.

Du L, Mahdi F, Jekabsons MB, Nagle DG, Zhou YD. Du L, et al. J Nat Prod. 2010 Nov 29;73(11):1868-72. doi: 10.1021/np100501n. Epub 2010 Oct 7. J Nat Prod. 2010. PMID: 20929261 Free PMC article.

2

Natural and semisynthetic mammea-type isoprenylated dihydroxycoumarins uncouple cellular respiration.

Du L, Mahdi F, Jekabsons MB, Nagle DG, Zhou YD. Du L, et al. J Nat Prod. 2011 Feb 25;74(2):240-8. doi: 10.1021/np100762s. Epub 2011 Jan 7. J Nat Prod. 2011. PMID: 21214226 Free PMC article.

3

Mitochondrial respiration inhibitors suppress protein translation and hypoxic signaling via the hyperphosphorylation and inactivation of translation initiation factor eIF2α and elongation factor eEF2.

Li J, Mahdi F, Du L, Datta S, Nagle DG, Zhou YD. Li J, et al. Among authors: du l. J Nat Prod. 2011 Sep 23;74(9):1894-901. doi: 10.1021/np200370z. Epub 2011 Aug 29. J Nat Prod. 2011. PMID: 21875114 Free PMC article.

4

Structures and mechanisms of antitumor agents: xestoquinones uncouple cellular respiration and disrupt HIF signaling in human breast tumor cells.

Du L, Mahdi F, Datta S, Jekabsons MB, Zhou YD, Nagle DG. Du L, et al. J Nat Prod. 2012 Sep 28;75(9):1553-9. doi: 10.1021/np3002892. Epub 2012 Aug 31. J Nat Prod. 2012. PMID: 22938093 Free PMC article.

5

Semisynthetic studies identify mitochondria poisons from botanical dietary supplements--geranyloxycoumarins from Aegle marmelos.

Li J, Mahdi F, Du L, Jekabsons MB, Zhou YD, Nagle DG. Li J, et al. Among authors: du l. Bioorg Med Chem. 2013 Apr 1;21(7):1795-803. doi: 10.1016/j.bmc.2013.01.048. Epub 2013 Feb 4. Bioorg Med Chem. 2013. PMID: 23434131 Free PMC article.

6

Inducers of hypoxic response: marine sesquiterpene quinones activate HIF-1.

Du L, Zhou YD, Nagle DG. Du L, et al. J Nat Prod. 2013 Jun 28;76(6):1175-81. doi: 10.1021/np400320r. Epub 2013 Jun 3. J Nat Prod. 2013. PMID: 23731014 Free PMC article.

7

Structures and potential antitumor activity of sesterterpenes from the marine sponge Hyrtios communis.

Li J, Du L, Kelly M, Zhou YD, Nagle DG. Li J, et al. Among authors: du l. J Nat Prod. 2013 Aug 23;76(8):1492-7. doi: 10.1021/np400350k. Epub 2013 Aug 14. J Nat Prod. 2013. PMID: 23944963 Free PMC article.

8

4',4‴,7,7″-tetra-O-methylcupressuflavone inhibits seed germination of Lactuca sativa.

DeForest JC, Du L, Joyner PM. DeForest JC, et al. Among authors: du l. J Nat Prod. 2014 Apr 25;77(4):1093-6. doi: 10.1021/np4010739. Epub 2014 Mar 14. J Nat Prod. 2014. PMID: 24628372

9

Cytotoxic dimeric epipolythiodiketopiperazines from the ascomycetous fungus Preussia typharum.

Du L, Robles AJ, King JB, Mooberry SL, Cichewicz RH. Du L, et al. J Nat Prod. 2014 Jun 27;77(6):1459-66. doi: 10.1021/np5002253. Epub 2014 Jun 3. J Nat Prod. 2014. PMID: 24893224 Free PMC article.

10

A potent HDAC inhibitor, 1-alaninechlamydocin, from a Tolypocladium sp. induces G2/M cell cycle arrest and apoptosis in MIA PaCa-2 cells.

Du L, Risinger AL, King JB, Powell DR, Cichewicz RH. Du L, et al. J Nat Prod. 2014 Jul 25;77(7):1753-7. doi: 10.1021/np500387h. Epub 2014 Jul 7. J Nat Prod. 2014. PMID: 24999749 Free PMC article.

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