Zhang J - Search Results

1

Endogenous oncogenic Nras mutation promotes aberrant GM-CSF signaling in granulocytic/monocytic precursors in a murine model of chronic myelomonocytic leukemia.

Wang J, Liu Y, Li Z, Du J, Ryu MJ, Taylor PR, Fleming MD, Young KH, Pitot H, Zhang J. Wang J, et al. Among authors: zhang j. Blood. 2010 Dec 23;116(26):5991-6002. doi: 10.1182/blood-2010-04-281527. Epub 2010 Oct 4. Blood. 2010. PMID: 20921338 Free PMC article.

2

Expression of oncogenic K-ras from its endogenous promoter leads to a partial block of erythroid differentiation and hyperactivation of cytokine-dependent signaling pathways.

Zhang J, Liu Y, Beard C, Tuveson DA, Jaenisch R, Jacks TE, Lodish HF. Zhang J, et al. Blood. 2007 Jun 15;109(12):5238-41. doi: 10.1182/blood-2006-09-047050. Epub 2007 Feb 22. Blood. 2007. PMID: 17317860 Free PMC article.

3

Oncogenic Kras-induced leukemogeneis: hematopoietic stem cells as the initial target and lineage-specific progenitors as the potential targets for final leukemic transformation.

Zhang J, Wang J, Liu Y, Sidik H, Young KH, Lodish HF, Fleming MD. Zhang J, et al. Blood. 2009 Feb 5;113(6):1304-14. doi: 10.1182/blood-2008-01-134262. Epub 2008 Dec 9. Blood. 2009. PMID: 19066392 Free PMC article.

4

Endogenous oncogenic Nras mutation initiates hematopoietic malignancies in a dose- and cell type-dependent manner.

Wang J, Liu Y, Li Z, Wang Z, Tan LX, Ryu MJ, Meline B, Du J, Young KH, Ranheim E, Chang Q, Zhang J. Wang J, et al. Among authors: zhang j. Blood. 2011 Jul 14;118(2):368-79. doi: 10.1182/blood-2010-12-326058. Epub 2011 May 17. Blood. 2011. PMID: 21586752 Free PMC article.

5

Distinct requirements of hematopoietic stem cell activity and Nras G12D signaling in different cell types during leukemogenesis.

Wang J, Liu Y, Tan LX, Lo JC, Du J, Ryu MJ, Ranheim EA, Zhang J. Wang J, et al. Among authors: zhang j. Cell Cycle. 2011 Sep 1;10(17):2836-9. doi: 10.4161/cc.10.17.17195. Epub 2011 Sep 1. Cell Cycle. 2011. PMID: 21857161 Free PMC article.

6

Oncogenic Kras expression in postmitotic neurons leads to S100A8-S100A9 protein overexpression and gliosis.

Ryu MJ, Liu Y, Zhong X, Du J, Peterson N, Kong G, Li H, Wang J, Salamat S, Chang Q, Zhang J. Ryu MJ, et al. Among authors: zhang j. J Biol Chem. 2012 Jun 29;287(27):22948-58. doi: 10.1074/jbc.M112.357772. Epub 2012 May 10. J Biol Chem. 2012. PMID: 22577135 Free PMC article.

7

Signaling profiling at the single-cell level identifies a distinct signaling signature in murine hematopoietic stem cells.

Du J, Wang J, Kong G, Jiang J, Zhang J, Liu Y, Tong W, Zhang J. Du J, et al. Among authors: zhang j. Stem Cells. 2012 Jul;30(7):1447-54. doi: 10.1002/stem.1127. Stem Cells. 2012. PMID: 22628264 Free PMC article.

8

Cis-element mutated in GATA2-dependent immunodeficiency governs hematopoiesis and vascular integrity.

Johnson KD, Hsu AP, Ryu MJ, Wang J, Gao X, Boyer ME, Liu Y, Lee Y, Calvo KR, Keles S, Zhang J, Holland SM, Bresnick EH. Johnson KD, et al. Among authors: zhang j. J Clin Invest. 2012 Oct;122(10):3692-704. doi: 10.1172/JCI61623. Epub 2012 Sep 10. J Clin Invest. 2012. PMID: 22996659 Free PMC article.

9

The IRP1-HIF-2α axis coordinates iron and oxygen sensing with erythropoiesis and iron absorption.

Anderson SA, Nizzi CP, Chang YI, Deck KM, Schmidt PJ, Galy B, Damnernsawad A, Broman AT, Kendziorski C, Hentze MW, Fleming MD, Zhang J, Eisenstein RS. Anderson SA, et al. Among authors: zhang j. Cell Metab. 2013 Feb 5;17(2):282-90. doi: 10.1016/j.cmet.2013.01.007. Cell Metab. 2013. PMID: 23395174 Free PMC article.

10

Notch1 gene mutations target KRAS G12D-expressing CD8+ cells and contribute to their leukemogenic transformation.

Kong G, Du J, Liu Y, Meline B, Chang YI, Ranheim EA, Wang J, Zhang J. Kong G, et al. Among authors: zhang j. J Biol Chem. 2013 Jun 21;288(25):18219-27. doi: 10.1074/jbc.M113.475376. Epub 2013 May 14. J Biol Chem. 2013. PMID: 23673656 Free PMC article.

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