De Clercq E - Search Results

1

2'-Azido-2',3'-dideoxythymidine: synthesis and crystal structure of a 2'-substituted dideoxynucleoside.

Van Aerschot A, Everaert D, Gosselin G, Peeters O, Blaton N, De Ranter C, Imbach JL, Balzarini J, De Clercq E, Herdewijn P. Van Aerschot A, et al. Among authors: de ranter c, de clercq e. Antiviral Res. 1990 Dec;14(6):357-69. doi: 10.1016/0166-3542(90)90054-b. Antiviral Res. 1990. PMID: 2088211

2

Particular characteristics of the anti-human cytomegalovirus activity of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC) in vitro.

Neyts J, Snoeck R, Balzarini J, De Clercq E. Neyts J, et al. Among authors: de clercq e. Antiviral Res. 1991 Jul;16(1):41-52. doi: 10.1016/0166-3542(91)90057-x. Antiviral Res. 1991. PMID: 1663729

3

Single-dose administration of 9-(2-phosphonylmethoxyethyl)adenine (PMEA) and 9-(2-phosphonylmethoxyethyl)-2,6-diaminopurine (PMEDAP) in the prophylaxis of retrovirus infection in vivo.

Naesens L, Balzarini J, De Clercq E. Naesens L, et al. Among authors: de clercq e. Antiviral Res. 1991 Jul;16(1):53-64. doi: 10.1016/0166-3542(91)90058-y. Antiviral Res. 1991. PMID: 1776876

4

Synthesis and biological evaluation of dinucleoside methylphosphonates of 3'-azido-3'-deoxythymidine and 2', 3'-dideoxycytidine.

Puech F, Gosselin G, Balzarini J, Good SS, Rideout JL, De Clercq E, Imbach JL. Puech F, et al. Among authors: de clercq e. Antiviral Res. 1990 Jul;14(1):11-23. doi: 10.1016/0166-3542(90)90062-c. Antiviral Res. 1990. PMID: 1964371

5

Synthesis and antiviral activity of 3'-heterocyclic substituted 3'-deoxythymidines.

Wigerinck P, Van Aerschot A, Janssen G, Claes P, Balzarini J, De Clercq E, Herdewijn P. Wigerinck P, et al. Among authors: de clercq e. J Med Chem. 1990 Feb;33(2):868-73. doi: 10.1021/jm00164a063. J Med Chem. 1990. PMID: 2299650

6

Synthesis and anti-HIV evaluation of 2',3'-dideoxyribo-5-chloropyrimidine analogues: reduced toxicity of 5-chlorinated 2',3'-dideoxynucleosides.

Van Aerschot A, Everaert D, Balzarini J, Augustyns K, Jie L, Janssen G, Peeters O, Blaton N, De Ranter C, De Clercq E, et al. Van Aerschot A, et al. Among authors: de ranter c, de clercq e. J Med Chem. 1990 Jun;33(6):1833-9. doi: 10.1021/jm00168a046. J Med Chem. 1990. PMID: 2342078

7

Alpha, beta- and beta, gamma-methylene 5'-phosphonate derivatives of 3'-azido-2',3'-dideoxythymidine-5'-triphosphate. Correlation between affinity for reverse transcriptase, susceptibility to hydrolysis by phosphodiesterases and anti-retrovirus activity.

Balzarini J, Herdewijn P, Pauwels R, Broder S, De Clercq E. Balzarini J, et al. Among authors: de clercq e. Biochem Pharmacol. 1988 Jun 15;37(12):2395-403. doi: 10.1016/0006-2952(88)90366-8. Biochem Pharmacol. 1988. PMID: 2455521

8

The antiviral activity of 9-beta-D-arabinofuranosyladenine is enhanced by the 2',3'-dideoxyriboside, the 2',3'-didehydro-2',3'-dideoxyriboside and the 3'-azido-2',3'-dideoxyriboside of 2,6-diaminopurine.

Balzarini J, De Clercq E. Balzarini J, et al. Among authors: de clercq e. Biochem Biophys Res Commun. 1989 Feb 28;159(1):61-7. doi: 10.1016/0006-291x(89)92404-2. Biochem Biophys Res Commun. 1989. PMID: 2538128

9

Differential patterns of intracellular metabolism of 2',3'-didehydro-2',3'-dideoxythymidine and 3'-azido-2',3'-dideoxythymidine, two potent anti-human immunodeficiency virus compounds.

Balzarini J, Herdewijn P, De Clercq E. Balzarini J, et al. Among authors: de clercq e. J Biol Chem. 1989 Apr 15;264(11):6127-33. J Biol Chem. 1989. PMID: 2539371 Free article.

10

Potentiating effect of ribavirin on the anti-retrovirus activity of 3'-azido-2,6-diaminopurine-2',3'-dideoxyriboside in vitro and in vivo.

Balzarini J, Herdewijn P, De Clercq E. Balzarini J, et al. Among authors: de clercq e. Antiviral Res. 1989 May-Jun;11(4):161-71. doi: 10.1016/0166-3542(89)90001-6. Antiviral Res. 1989. PMID: 2545163

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