Smrcka AV - Search Results

1

Rational design of a selective covalent modifier of G protein βγ subunits.

Dessal AL, Prades R, Giralt E, Smrcka AV. Dessal AL, et al. Among authors: smrcka av. Mol Pharmacol. 2011 Jan;79(1):24-33. doi: 10.1124/mol.110.068155. Epub 2010 Sep 29. Mol Pharmacol. 2011. PMID: 20881007 Free PMC article.

2

G protein beta 5 subunit interactions with alpha subunits and effectors.

Yoshikawa DM, Hatwar M, Smrcka AV. Yoshikawa DM, et al. Among authors: smrcka av. Biochemistry. 2000 Sep 19;39(37):11340-7. doi: 10.1021/bi0005557. Biochemistry. 2000. PMID: 10985779

3

Assay for G protein-dependent activation of phospholipase C beta using purified protein components.

Ghosh M, Smrcka AV. Ghosh M, et al. Among authors: smrcka av. Methods Mol Biol. 2004;237:67-75. doi: 10.1385/1-59259-430-1:67. Methods Mol Biol. 2004. PMID: 14501039 Review.

4

Ric-8 enhances G protein betagamma-dependent signaling in response to betagamma-binding peptides in intact cells.

Malik S, Ghosh M, Bonacci TM, Tall GG, Smrcka AV. Malik S, et al. Among authors: smrcka av. Mol Pharmacol. 2005 Jul;68(1):129-36. doi: 10.1124/mol.104.010116. Epub 2005 Mar 31. Mol Pharmacol. 2005. PMID: 15802611

5

Differential targeting of Gbetagamma-subunit signaling with small molecules.

Bonacci TM, Mathews JL, Yuan C, Lehmann DM, Malik S, Wu D, Font JL, Bidlack JM, Smrcka AV. Bonacci TM, et al. Among authors: smrcka av. Science. 2006 Apr 21;312(5772):443-6. doi: 10.1126/science.1120378. Science. 2006. PMID: 16627746

6

Signaling by a non-dissociated complex of G protein βγ and α subunits stimulated by a receptor-independent activator of G protein signaling, AGS8.

Yuan C, Sato M, Lanier SM, Smrcka AV. Yuan C, et al. Among authors: smrcka av. J Biol Chem. 2007 Jul 6;282(27):19938-47. doi: 10.1074/jbc.M700396200. Epub 2007 Apr 19. J Biol Chem. 2007. PMID: 17446173 Free article.

7

Small molecule disruption of G protein beta gamma subunit signaling inhibits neutrophil chemotaxis and inflammation.

Lehmann DM, Seneviratne AM, Smrcka AV. Lehmann DM, et al. Among authors: smrcka av. Mol Pharmacol. 2008 Feb;73(2):410-8. doi: 10.1124/mol.107.041780. Epub 2007 Nov 15. Mol Pharmacol. 2008. PMID: 18006643 Free PMC article.

8

G protein βγ subunits: central mediators of G protein-coupled receptor signaling.

Smrcka AV. Smrcka AV. Cell Mol Life Sci. 2008 Jul;65(14):2191-214. doi: 10.1007/s00018-008-8006-5. Cell Mol Life Sci. 2008. PMID: 18488142 Free PMC article. Review.

9

G protein betagamma subunits as targets for small molecule therapeutic development.

Smrcka AV, Lehmann DM, Dessal AL. Smrcka AV, et al. Comb Chem High Throughput Screen. 2008 Jun;11(5):382-95. doi: 10.2174/138620708784534761. Comb Chem High Throughput Screen. 2008. PMID: 18537559 Free PMC article. Review.

10

Evaluating docking methods for prediction of binding affinities of small molecules to the G protein betagamma subunits.

Park MS, Dessal AL, Smrcka AV, Stern HA. Park MS, et al. Among authors: smrcka av. J Chem Inf Model. 2009 Feb;49(2):437-43. doi: 10.1021/ci800384q. J Chem Inf Model. 2009. PMID: 19434844 Free PMC article.

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