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Characterization of a site on PAI-1 that binds to vitronectin outside of the somatomedin B domain.
Schar CR, Jensen JK, Christensen A, Blouse GE, Andreasen PA, Peterson CB. Schar CR, et al. J Biol Chem. 2008 Oct 17;283(42):28487-96. doi: 10.1074/jbc.M804257200. Epub 2008 Jul 24. J Biol Chem. 2008. PMID: 18658131 Free PMC article.
A strategy for deletion mutagenesis that removes the SMB domain demonstrates that this mutant form of vitronectin retains PAI-1 binding (Schar, C. R., Blouse, G. E., Minor, K. M., and Peterson, C. B. (2008) J. Biol. Chem. 283, 10297-10309). ...
A strategy for deletion mutagenesis that removes the SMB domain demonstrates that this mutant form of vitronectin retains PAI-1 binding ( …
Interactions of plasminogen activator inhibitor-1 with vitronectin involve an extensive binding surface and induce mutual conformational rearrangements.
Blouse GE, Dupont DM, Schar CR, Jensen JK, Minor KH, Anagli JY, Gårdsvoll H, Ploug M, Peterson CB, Andreasen PA. Blouse GE, et al. Biochemistry. 2009 Mar 3;48(8):1723-35. doi: 10.1021/bi8017015. Biochemistry. 2009. PMID: 19193026
In support of this model are recent results that define a PAI-1-binding site on vitronectin that lies outside the somatomedin B domain (Schar, C. R., Blouse, G. E., Minor, K. H., and Peterson, C. B. (2008) J. Biol. Chem. 283, 10297-10309) and the complementar …
In support of this model are recent results that define a PAI-1-binding site on vitronectin that lies outside the somatomedin B domain (S …
29 results