Protein kinase C mediates the inhibitory effect of substance P on HCO3- secretion from guinea pig pancreatic ducts.
Hegyi P, Rakonczay Z Jr, Tiszlavicz L, Varró A, Tóth A, Rácz G, Varga G, Gray MA, Argent BE.
Hegyi P, et al.
Am J Physiol Cell Physiol. 2005 May;288(5):C1030-41. doi: 10.1152/ajpcell.00430.2003. Epub 2004 Dec 29.
Am J Physiol Cell Physiol. 2005.
PMID: 15625303
Free article.
The inhibitory control of pancreatic ductal HCO(3)(-) secretion may be physiologically important in terms of limiting the hydrostatic pressure developed within the ducts and in terms of switching off pancreatic secretion after a meal. Substance P (SP) inhibits secretin-sti …
The inhibitory control of pancreatic ductal HCO(3)(-) secretion may be physiologically important in terms of limiting the hydrostatic pressu …