LeCluyse EL - Search Results

1

Evaluation of an in vitro toxicogenetic mouse model for hepatotoxicity.

Martinez SM, Bradford BU, Soldatow VY, Kosyk O, Sandot A, Witek R, Kaiser R, Stewart T, Amaral K, Freeman K, Black C, LeCluyse EL, Ferguson SS, Rusyn I. Martinez SM, et al. Among authors: lecluyse el. Toxicol Appl Pharmacol. 2010 Dec 15;249(3):208-16. doi: 10.1016/j.taap.2010.09.012. Epub 2010 Sep 24. Toxicol Appl Pharmacol. 2010. PMID: 20869979 Free PMC article.

2

In vitro models for liver toxicity testing.

Soldatow VY, Lecluyse EL, Griffith LG, Rusyn I. Soldatow VY, et al. Among authors: lecluyse el. Toxicol Res (Camb). 2013 Jan 1;2(1):23-39. doi: 10.1039/C2TX20051A. Epub 2012 Nov 23. Toxicol Res (Camb). 2013. PMID: 23495363 Free PMC article.

3

Xenobiotic-metabolizing enzyme and transporter gene expression in primary cultures of human hepatocytes modulated by ToxCast chemicals.

Rotroff DM, Beam AL, Dix DJ, Farmer A, Freeman KM, Houck KA, Judson RS, LeCluyse EL, Martin MT, Reif DM, Ferguson SS. Rotroff DM, et al. Among authors: lecluyse el. J Toxicol Environ Health B Crit Rev. 2010 Feb;13(2-4):329-46. doi: 10.1080/10937404.2010.483949. J Toxicol Environ Health B Crit Rev. 2010. PMID: 20574906

4

Organotypic liver culture models: meeting current challenges in toxicity testing.

LeCluyse EL, Witek RP, Andersen ME, Powers MJ. LeCluyse EL, et al. Crit Rev Toxicol. 2012 Jul;42(6):501-48. doi: 10.3109/10408444.2012.682115. Epub 2012 May 15. Crit Rev Toxicol. 2012. PMID: 22582993 Free PMC article. Review.

5

Long-Term Engineered Cultures of Primary Mouse Hepatocytes for Strain and Species Comparison Studies During Drug Development.

Ware BR, Brown GE, Soldatow VY, LeCluyse EL, Khetani SR. Ware BR, et al. Among authors: lecluyse el. Gene Expr. 2019 Nov 4;19(3):199-214. doi: 10.3727/105221619X15638857793317. Epub 2019 Jul 24. Gene Expr. 2019. PMID: 31340881 Free PMC article.

6

Human CYP2C8 is transcriptionally regulated by the nuclear receptors constitutive androstane receptor, pregnane X receptor, glucocorticoid receptor, and hepatic nuclear factor 4alpha.

Ferguson SS, Chen Y, LeCluyse EL, Negishi M, Goldstein JA. Ferguson SS, et al. Among authors: lecluyse el. Mol Pharmacol. 2005 Sep;68(3):747-57. doi: 10.1124/mol.105.013169. Epub 2005 Jun 2. Mol Pharmacol. 2005. PMID: 15933212

7

Cross-species comparisons of transcriptomic alterations in human and rat primary hepatocytes exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin.

Black MB, Budinsky RA, Dombkowski A, Cukovic D, LeCluyse EL, Ferguson SS, Thomas RS, Rowlands JC. Black MB, et al. Among authors: lecluyse el. Toxicol Sci. 2012 May;127(1):199-215. doi: 10.1093/toxsci/kfs069. Epub 2012 Feb 1. Toxicol Sci. 2012. PMID: 22298810

8

Knockout of the aryl hydrocarbon receptor results in distinct hepatic and renal phenotypes in rats and mice.

Harrill JA, Hukkanen RR, Lawson M, Martin G, Gilger B, Soldatow V, Lecluyse EL, Budinsky RA, Rowlands JC, Thomas RS. Harrill JA, et al. Among authors: lecluyse el. Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13. Toxicol Appl Pharmacol. 2013. PMID: 23859880

9

Development of an In Vitro Human Thyroid Microtissue Model for Chemical Screening.

Deisenroth C, Soldatow VY, Ford J, Stewart W, Brinkman C, LeCluyse EL, MacMillan DK, Thomas RS. Deisenroth C, et al. Among authors: lecluyse el. Toxicol Sci. 2020 Mar 1;174(1):63-78. doi: 10.1093/toxsci/kfz238. Toxicol Sci. 2020. PMID: 31808822 Free PMC article.

10

Regulation of human CYP2C9 by the constitutive androstane receptor: discovery of a new distal binding site.

Ferguson SS, LeCluyse EL, Negishi M, Goldstein JA. Ferguson SS, et al. Among authors: lecluyse el. Mol Pharmacol. 2002 Sep;62(3):737-46. doi: 10.1124/mol.62.3.737. Mol Pharmacol. 2002. PMID: 12181452

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

125 results

Search Page

Filters