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NOTCH1 and FBXW7 mutations have a favorable impact on early response to treatment, but not on outcome, in children with T-cell acute lymphoblastic leukemia (T-ALL) treated on EORTC trials 58881 and 58951.
Clappier E, Collette S, Grardel N, Girard S, Suarez L, Brunie G, Kaltenbach S, Yakouben K, Mazingue F, Robert A, Boutard P, Plantaz D, Rohrlich P, van Vlierberghe P, Preudhomme C, Otten J, Speleman F, Dastugue N, Suciu S, Benoit Y, Bertrand Y, Cavé H; EORTC-CLG. Clappier E, et al. Among authors: kaltenbach s. Leukemia. 2010 Dec;24(12):2023-31. doi: 10.1038/leu.2010.205. Epub 2010 Sep 23. Leukemia. 2010. PMID: 20861920 Clinical Trial.
Hemifacial myohyperplasia is due to somatic muscular PIK3CA gain-of-function mutations and responds to pharmacological inhibition.
Bayard C, Segna E, Taverne M, Fraissenon A, Hennocq Q, Periou B, Zerbib L, Ladraa S, Chapelle C, Hoguin C, Kaltenbach S, Villarese P, Asnafi V, Broissand C, Nemazanyy I, Autret G, Goudin N, Legendre C, Authier FJ, Viel T, Tavitian B, Gitiaux C, Fraitag S, Duong JP, Delcros C, Sergent B, Picard A, Dussiot M, Guibaud L, Khonsari R, Canaud G. Bayard C, et al. Among authors: kaltenbach s. J Exp Med. 2023 Nov 6;220(11):e20230926. doi: 10.1084/jem.20230926. Epub 2023 Sep 15. J Exp Med. 2023. PMID: 37712948 Free PMC article.
Targeted therapy for capillary-venous malformations.
Zerbib L, Ladraa S, Fraissenon A, Bayard C, Firpion M, Venot Q, Protic S, Hoguin C, Thomas A, Fraitag S, Duong JP, Kaltenbach S, Balducci E, Lefevre C, Villarese P, Asnafi V, Broissand C, Goudin N, Nemazanyy I, Autret G, Tavitian B, Legendre C, Arzouk N, Minard-Colin V, Chopinet C, Dussiot M, Adams DM, Mirault T, Guibaud L, Isenring P, Canaud G. Zerbib L, et al. Among authors: kaltenbach s. Signal Transduct Target Ther. 2024 Jun 17;9(1):146. doi: 10.1038/s41392-024-01862-9. Signal Transduct Target Ther. 2024. PMID: 38880808 Free PMC article.
PIK3CA-Related Disorders: From Disease Mechanism to Evidence-Based Treatments.
Morin GM, Zerbib L, Kaltenbach S, Fraissenon A, Balducci E, Asnafi V, Canaud G. Morin GM, et al. Among authors: kaltenbach s. Annu Rev Genomics Hum Genet. 2024 Aug;25(1):211-237. doi: 10.1146/annurev-genom-121222-114518. Epub 2024 Aug 6. Annu Rev Genomics Hum Genet. 2024. PMID: 38316164 Review.
Inflammation is predictive of outcome in Waldenström macroglobulinemia treated by Bruton tyrosine kinase inhibitors: a multicentric real-life study.
Debureaux PE, Forgeard N, Elessa D, Harel S, Frenzel L, Royer B, Talbot A, Choquet S, Davi F, Nguyen-Khac F, Cuccuini W, Cheminant M, Bravetti C, Lazarian G, Kaltenbach S, Hermine O, Roos-Weil D, Espéli M, Balabanian K, Arnulf B. Debureaux PE, et al. Among authors: kaltenbach s. Haematologica. 2024 Jan 1;109(1):325-330. doi: 10.3324/haematol.2023.283141. Haematologica. 2024. PMID: 37584289 Free PMC article. No abstract available.
Wilms tumor 1 (WT1) gene mutations in pediatric T-cell malignancies.
Renneville A, Kaltenbach S, Clappier E, Collette S, Micol JB, Nelken B, Lepelley P, Dastugue N, Benoît Y, Bertrand Y, Preudhomme C, Cavé H. Renneville A, et al. Among authors: kaltenbach s. Leukemia. 2010 Feb;24(2):476-80. doi: 10.1038/leu.2009.221. Epub 2009 Oct 22. Leukemia. 2010. PMID: 19847202 No abstract available.
Activating mutation in the TSLPR gene in B-cell precursor lymphoblastic leukemia.
Chapiro E, Russell L, Lainey E, Kaltenbach S, Ragu C, Della-Valle V, Hanssens K, Macintyre EA, Radford-Weiss I, Delabesse E, Cavé H, Mercher T, Harrison CJ, Nguyen-Khac F, Dubreuil P, Bernard OA. Chapiro E, et al. Among authors: kaltenbach s. Leukemia. 2010 Mar;24(3):642-5. doi: 10.1038/leu.2009.231. Epub 2009 Nov 12. Leukemia. 2010. PMID: 19907440 No abstract available.
Genetic typing of CBL, ASXL1, RUNX1, TET2 and JAK2 in juvenile myelomonocytic leukaemia reveals a genetic profile distinct from chronic myelomonocytic leukaemia.
Pérez B, Kosmider O, Cassinat B, Renneville A, Lachenaud J, Kaltenbach S, Bertrand Y, Baruchel A, Chomienne C, Fontenay M, Preudhomme C, Cavé H. Pérez B, et al. Among authors: kaltenbach s. Br J Haematol. 2010 Dec;151(5):460-8. doi: 10.1111/j.1365-2141.2010.08393.x. Epub 2010 Oct 19. Br J Haematol. 2010. PMID: 20955399 Free article.
Sustained leukemia-free state and molecular response to sorafenib in a patient with chronic myelomonocytic leukemia in transformation driven by homozygous FLT3-ITD malignant hematopoiesis.
Kosmider O, Chapuis N, Kaltenbach S, Coriat R, Boudou Rouquette P, Willems L, Chesnais V, Radford-Weiss I, Bardet V, Mayeux P, Tamburini J, Fontenay M, Bouscary D. Kosmider O, et al. Among authors: kaltenbach s. Clin Lymphoma Myeloma Leuk. 2013 Jun;13(3):347-50. doi: 10.1016/j.clml.2012.11.007. Clin Lymphoma Myeloma Leuk. 2013. PMID: 23246161 No abstract available.
75 results