Garner AL - Search Results

1

cat-ELCCA: a robust method to monitor the fatty acid acyltransferase activity of ghrelin O-acyltransferase (GOAT).

Garner AL, Janda KD. Garner AL, et al. Angew Chem Int Ed Engl. 2010 Dec 10;49(50):9630-4. doi: 10.1002/anie.201003387. Angew Chem Int Ed Engl. 2010. PMID: 20845345 Free PMC article.

2

Shedding light on the ghrelin/GOAT metabolism saga.

Garner AL, Janda KD. Garner AL, et al. Chembiochem. 2011 Mar 7;12(4):523-5. doi: 10.1002/cbic.201000777. Epub 2011 Jan 20. Chembiochem. 2011. PMID: 21254317

3

A small molecule antagonist of ghrelin O-acyltransferase (GOAT).

Garner AL, Janda KD. Garner AL, et al. Chem Commun (Camb). 2011 Jul 14;47(26):7512-4. doi: 10.1039/c1cc11817j. Epub 2011 May 19. Chem Commun (Camb). 2011. PMID: 21594284

4

Repositioning of an existing drug for the neglected tropical disease Onchocerciasis.

Gloeckner C, Garner AL, Mersha F, Oksov Y, Tricoche N, Eubanks LM, Lustigman S, Kaufmann GF, Janda KD. Gloeckner C, et al. Among authors: garner al. Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3424-9. doi: 10.1073/pnas.0915125107. Epub 2010 Feb 8. Proc Natl Acad Sci U S A. 2010. PMID: 20142509 Free PMC article.

5

Synthesis of 'clickable' acylhomoserine lactone quorum sensing probes: unanticipated effects on mammalian cell activation.

Garner AL, Yu J, Struss AK, Lowery CA, Zhu J, Kim SK, Park J, Mayorov AV, Kaufmann GF, Kravchenko VV, Janda KD. Garner AL, et al. Bioorg Med Chem Lett. 2011 May 1;21(9):2702-5. doi: 10.1016/j.bmcl.2010.11.122. Epub 2010 Dec 4. Bioorg Med Chem Lett. 2011. PMID: 21190852 Free PMC article.

6

Protein-protein interactions and cancer: targeting the central dogma.

Garner AL, Janda KD. Garner AL, et al. Curr Top Med Chem. 2011;11(3):258-80. doi: 10.2174/156802611794072614. Curr Top Med Chem. 2011. PMID: 21320057 Review.

7

Design, synthesis, and biological activities of closantel analogues: structural promiscuity and its impact on Onchocerca volvulus.

Garner AL, Gloeckner C, Tricoche N, Zakhari JS, Samje M, Cho-Ngwa F, Lustigman S, Janda KD. Garner AL, et al. J Med Chem. 2011 Jun 9;54(11):3963-72. doi: 10.1021/jm200364n. Epub 2011 May 12. J Med Chem. 2011. PMID: 21534605

8

A multivalent probe for AI-2 quorum-sensing receptors.

Garner AL, Park J, Zakhari JS, Lowery CA, Struss AK, Sawada D, Kaufmann GF, Janda KD. Garner AL, et al. J Am Chem Soc. 2011 Oct 12;133(40):15934-7. doi: 10.1021/ja207556d. Epub 2011 Sep 15. J Am Chem Soc. 2011. PMID: 21913711 Free PMC article.

9

3-Hydroxy-1-alkyl-2-methylpyridine-4(1H)-thiones: Inhibition of the Pseudomonas aeruginosa Virulence Factor LasB.

Garner AL, Struss AK, Fullagar JL, Agrawal A, Moreno AY, Cohen SM, Janda KD. Garner AL, et al. ACS Med Chem Lett. 2012 Aug 9;3(8):668-672. doi: 10.1021/ml300128f. Epub 2012 Jun 19. ACS Med Chem Lett. 2012. PMID: 23181168 Free PMC article.

10

Immunomodulation and the quorum sensing molecule 3-oxo-C12-homoserine lactone: the importance of chemical scaffolding for probe development.

Garner AL, Yu J, Struss AK, Kaufmann GF, Kravchenko VV, Janda KD. Garner AL, et al. Chem Commun (Camb). 2013 Feb 21;49(15):1515-7. doi: 10.1039/c3cc38851d. Chem Commun (Camb). 2013. PMID: 23328974 Free PMC article.

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