Houghton AN - Search Results

1

Alphavirus replicon particles expressing TRP-2 provide potent therapeutic effect on melanoma through activation of humoral and cellular immunity.

Avogadri F, Merghoub T, Maughan MF, Hirschhorn-Cymerman D, Morris J, Ritter E, Olmsted R, Houghton AN, Wolchok JD. Avogadri F, et al. Among authors: houghton an. PLoS One. 2010 Sep 10;5(9):e12670. doi: 10.1371/journal.pone.0012670. PLoS One. 2010. PMID: 20844763 Free PMC article.

2

Comparison of two cancer vaccines targeting tyrosinase: plasmid DNA and recombinant alphavirus replicon particles.

Goldberg SM, Bartido SM, Gardner JP, Guevara-Patiño JA, Montgomery SC, Perales MA, Maughan MF, Dempsey J, Donovan GP, Olson WC, Houghton AN, Wolchok JD. Goldberg SM, et al. Among authors: houghton an. Clin Cancer Res. 2005 Nov 15;11(22):8114-21. doi: 10.1158/1078-0432.CCR-05-1410. Clin Cancer Res. 2005. PMID: 16299244

3

Improved tumor immunity using anti-tyrosinase related protein-1 monoclonal antibody combined with DNA vaccines in murine melanoma.

Saenger YM, Li Y, Chiou KC, Chan B, Rizzuto G, Terzulli SL, Merghoub T, Houghton AN, Wolchok JD. Saenger YM, et al. Among authors: houghton an. Cancer Res. 2008 Dec 1;68(23):9884-91. doi: 10.1158/0008-5472.CAN-08-2233. Cancer Res. 2008. PMID: 19047169 Free PMC article.

4

OX40 engagement and chemotherapy combination provides potent antitumor immunity with concomitant regulatory T cell apoptosis.

Hirschhorn-Cymerman D, Rizzuto GA, Merghoub T, Cohen AD, Avogadri F, Lesokhin AM, Weinberg AD, Wolchok JD, Houghton AN. Hirschhorn-Cymerman D, et al. Among authors: houghton an. J Exp Med. 2009 May 11;206(5):1103-16. doi: 10.1084/jem.20082205. Epub 2009 May 4. J Exp Med. 2009. PMID: 19414558 Free PMC article.

5

Agonist anti-GITR monoclonal antibody induces melanoma tumor immunity in mice by altering regulatory T cell stability and intra-tumor accumulation.

Cohen AD, Schaer DA, Liu C, Li Y, Hirschhorn-Cymmerman D, Kim SC, Diab A, Rizzuto G, Duan F, Perales MA, Merghoub T, Houghton AN, Wolchok JD. Cohen AD, et al. Among authors: houghton an. PLoS One. 2010 May 3;5(5):e10436. doi: 10.1371/journal.pone.0010436. PLoS One. 2010. PMID: 20454651 Free PMC article.

6

Detection of intra-tumor self antigen recognition during melanoma tumor progression in mice using advanced multimode confocal/two photon microscope.

Schaer DA, Li Y, Merghoub T, Rizzuto GA, Shemesh A, Cohen AD, Li Y, Avogadri F, Toledo-Crow R, Houghton AN, Wolchok JD. Schaer DA, et al. Among authors: houghton an. PLoS One. 2011;6(6):e21214. doi: 10.1371/journal.pone.0021214. Epub 2011 Jun 22. PLoS One. 2011. PMID: 21731676 Free PMC article.

7

Monocytic CCR2(+) myeloid-derived suppressor cells promote immune escape by limiting activated CD8 T-cell infiltration into the tumor microenvironment.

Lesokhin AM, Hohl TM, Kitano S, Cortez C, Hirschhorn-Cymerman D, Avogadri F, Rizzuto GA, Lazarus JJ, Pamer EG, Houghton AN, Merghoub T, Wolchok JD. Lesokhin AM, et al. Among authors: houghton an. Cancer Res. 2012 Feb 15;72(4):876-86. doi: 10.1158/0008-5472.CAN-11-1792. Epub 2011 Dec 15. Cancer Res. 2012. PMID: 22174368 Free PMC article.

8

Enhanced responses to tumor immunization following total body irradiation are time-dependent.

Diab A, Jenq RR, Rizzuto GA, Cohen AD, Huggins DW, Merghoub T, Engelhorn ME, Guevara-Patiño JA, Suh D, Hubbard-Lucey VM, Kochman AA, Chen S, Zhong H, Wolchok JD, van den Brink MR, Houghton AN, Perales MA. Diab A, et al. Among authors: houghton an. PLoS One. 2013 Dec 12;8(12):e82496. doi: 10.1371/journal.pone.0082496. eCollection 2013. PLoS One. 2013. PMID: 24349298 Free PMC article.

9

Induction of autoantibodies against tyrosinase-related proteins following DNA vaccination: unexpected reactivity to a protein paralogue.

Srinivasan R, Houghton AN, Wolchok JD. Srinivasan R, et al. Among authors: houghton an. Cancer Immun. 2002 Jul 19;2:8. Cancer Immun. 2002. PMID: 12747753

10

Immunity to melanoma: unraveling the relation of tumor immunity and autoimmunity.

Ramirez-Montagut T, Turk MJ, Wolchok JD, Guevara-Patino JA, Houghton AN. Ramirez-Montagut T, et al. Among authors: houghton an. Oncogene. 2003 May 19;22(20):3180-7. doi: 10.1038/sj.onc.1206462. Oncogene. 2003. PMID: 12789294 Review.

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