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Page 1
Azabenzthiazole inhibitors of leukotriene A₄ hydrolase.
Tanis VM, Bacani GM, Blevitt JM, Chrovian CC, Crawford S, De Leon A, Fourie AM, Gomez L, Grice CA, Herman K, Kearney AM, Landry-Bayle AM, Lee-Dutra A, Nelson J, Riley JP, Santillán A Jr, Wiener JJ, Xue X, Young AL. Tanis VM, et al. Among authors: santillan a jr. Bioorg Med Chem Lett. 2012 Dec 15;22(24):7504-11. doi: 10.1016/j.bmcl.2012.10.036. Epub 2012 Oct 17. Bioorg Med Chem Lett. 2012. PMID: 23127888
Indole- and benzothiophene-based histamine H3 antagonists.
Santillan A Jr, McClure KJ, Allison BD, Lord B, Boggs JD, Morton KL, Everson AM, Nepomuceno D, Letavic MA, Lee-Dutra A, Lovenberg TW, Carruthers NI, Grice CA. Santillan A Jr, et al. Bioorg Med Chem Lett. 2010 Nov 1;20(21):6226-30. doi: 10.1016/j.bmcl.2010.08.103. Epub 2010 Aug 27. Bioorg Med Chem Lett. 2010. PMID: 20843691
Tetrahydroindazole inhibitors of bacterial type II topoisomerases. Part 2: SAR development and potency against multidrug-resistant strains.
Wiener JJ, Gomez L, Venkatesan H, Santillán A Jr, Allison BD, Schwarz KL, Shinde S, Tang L, Hack MD, Morrow BJ, Motley ST, Goldschmidt RM, Shaw KJ, Jones TK, Grice CA. Wiener JJ, et al. Among authors: santillan a jr. Bioorg Med Chem Lett. 2007 May 15;17(10):2718-22. doi: 10.1016/j.bmcl.2007.03.004. Epub 2007 Mar 6. Bioorg Med Chem Lett. 2007. PMID: 17382544
Synthesis and evaluation of 1,2,8, 8a-Tetrahydrocyclopropa[c]pyrrolo[3,2-e]indol-4(5H)-one, the parent alkylation subunit of CC-1065 and the duocarmycins: impact of the alkylation subunit substituents and its implications for DNA alkylation catalysis.
Boger DL, Santillán A Jr, Searcey M, Brunette SR, Wolkenberg SE, Hedrick MP, Jin Q. Boger DL, et al. Among authors: santillan a jr. J Org Chem. 2000 Jun 30;65(13):4101-11. doi: 10.1021/jo000297j. J Org Chem. 2000. PMID: 10866627
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