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The vent-like homeobox gene VENTX promotes human myeloid differentiation and is highly expressed in acute myeloid leukemia.
Rawat VP, Arseni N, Ahmed F, Mulaw MA, Thoene S, Heilmeier B, Sadlon T, D'Andrea RJ, Hiddemann W, Bohlander SK, Buske C, Feuring-Buske M. Rawat VP, et al. Among authors: hiddemann w. Proc Natl Acad Sci U S A. 2010 Sep 28;107(39):16946-51. doi: 10.1073/pnas.1001878107. Epub 2010 Sep 10. Proc Natl Acad Sci U S A. 2010. PMID: 20833819 Free PMC article.
Ectopic expression of the homeobox gene Cdx2 is the transforming event in a mouse model of t(12;13)(p13;q12) acute myeloid leukemia.
Rawat VP, Cusan M, Deshpande A, Hiddemann W, Quintanilla-Martinez L, Humphries RK, Bohlander SK, Feuring-Buske M, Buske C. Rawat VP, et al. Among authors: hiddemann w. Proc Natl Acad Sci U S A. 2004 Jan 20;101(3):817-22. doi: 10.1073/pnas.0305555101. Epub 2004 Jan 12. Proc Natl Acad Sci U S A. 2004. PMID: 14718672 Free PMC article.
Overexpression of CDX2 perturbs HOX gene expression in murine progenitors depending on its N-terminal domain and is closely correlated with deregulated HOX gene expression in human acute myeloid leukemia.
Rawat VP, Thoene S, Naidu VM, Arseni N, Heilmeier B, Metzeler K, Petropoulos K, Deshpande A, Quintanilla-Martinez L, Bohlander SK, Spiekermann K, Hiddemann W, Feuring-Buske M, Buske C. Rawat VP, et al. Among authors: hiddemann w. Blood. 2008 Jan 1;111(1):309-19. doi: 10.1182/blood-2007-04-085407. Epub 2007 Sep 12. Blood. 2008. PMID: 17855634 Free article.
The AML1-ETO fusion gene and the FLT3 length mutation collaborate in inducing acute leukemia in mice.
Schessl C, Rawat VP, Cusan M, Deshpande A, Kohl TM, Rosten PM, Spiekermann K, Humphries RK, Schnittger S, Kern W, Hiddemann W, Quintanilla-Martinez L, Bohlander SK, Feuring-Buske M, Buske C. Schessl C, et al. Among authors: hiddemann w. J Clin Invest. 2005 Aug;115(8):2159-68. doi: 10.1172/JCI24225. Epub 2005 Jul 14. J Clin Invest. 2005. PMID: 16025155 Free PMC article.
Acute myeloid leukemia is propagated by a leukemic stem cell with lymphoid characteristics in a mouse model of CALM/AF10-positive leukemia.
Deshpande AJ, Cusan M, Rawat VP, Reuter H, Krause A, Pott C, Quintanilla-Martinez L, Kakadia P, Kuchenbauer F, Ahmed F, Delabesse E, Hahn M, Lichter P, Kneba M, Hiddemann W, Macintyre E, Mecucci C, Ludwig WD, Humphries RK, Bohlander SK, Feuring-Buske M, Buske C. Deshpande AJ, et al. Among authors: hiddemann w. Cancer Cell. 2006 Nov;10(5):363-74. doi: 10.1016/j.ccr.2006.08.023. Cancer Cell. 2006. PMID: 17097559 Free article.
[Pathobiology of acute myeloid leukemia].
Christ O, Feuring-Buske M, Hiddemann W, Buske C. Christ O, et al. Among authors: hiddemann w. Med Klin (Munich). 2007 Apr 15;102(4):290-5. doi: 10.1007/s00063-007-1035-2. Med Klin (Munich). 2007. PMID: 17426932 Review. German.
A novel role for Lef-1, a central transcription mediator of Wnt signaling, in leukemogenesis.
Petropoulos K, Arseni N, Schessl C, Stadler CR, Rawat VP, Deshpande AJ, Heilmeier B, Hiddemann W, Quintanilla-Martinez L, Bohlander SK, Feuring-Buske M, Buske C. Petropoulos K, et al. Among authors: hiddemann w. J Exp Med. 2008 Mar 17;205(3):515-22. doi: 10.1084/jem.20071875. Epub 2008 Mar 3. J Exp Med. 2008. PMID: 18316418 Free PMC article.
916 results