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Targeting mitochondrial glutaminase activity inhibits oncogenic transformation.
Wang JB, Erickson JW, Fuji R, Ramachandran S, Gao P, Dinavahi R, Wilson KF, Ambrosio AL, Dias SM, Dang CV, Cerione RA. Wang JB, et al. Among authors: ambrosio al. Cancer Cell. 2010 Sep 14;18(3):207-19. doi: 10.1016/j.ccr.2010.08.009. Cancer Cell. 2010. PMID: 20832749 Free PMC article.
Mitochondrial localization and structure-based phosphate activation mechanism of Glutaminase C with implications for cancer metabolism.
Cassago A, Ferreira AP, Ferreira IM, Fornezari C, Gomes ER, Greene KS, Pereira HM, Garratt RC, Dias SM, Ambrosio AL. Cassago A, et al. Among authors: ambrosio al. Proc Natl Acad Sci U S A. 2012 Jan 24;109(4):1092-7. doi: 10.1073/pnas.1112495109. Epub 2012 Jan 6. Proc Natl Acad Sci U S A. 2012. PMID: 22228304 Free PMC article.
Structure and activation mechanism of the human liver-type glutaminase GLS2.
Ferreira IM, Quesñay JEN, Bastos AC, Rodrigues CT, Vollmar M, Krojer T, Strain-Damerell C, Burgess-Brown NA, von Delft F, Yue WW, Dias SM, Ambrosio AL. Ferreira IM, et al. Among authors: ambrosio al. Biochimie. 2021 Jun;185:96-104. doi: 10.1016/j.biochi.2021.03.009. Epub 2021 Mar 18. Biochimie. 2021. PMID: 33746066 Free PMC article.
High-Throughput Screening Reveals New Glutaminase Inhibitor Molecules.
E Costa RK, Rodrigues CT, H Campos JC, Paradela LS, Dias MM, Novaes da Silva B, de Valega Negrao CVZ, Gonçalves KA, Ascenção CFR, Adamoski D, Mercaldi GF, Bastos ACS, Batista FAH, Figueira AC, Cordeiro AT, Ambrosio ALB, Guido RVC, Dias SMG. E Costa RK, et al. Among authors: ambrosio alb. ACS Pharmacol Transl Sci. 2021 Dec 1;4(6):1849-1866. doi: 10.1021/acsptsci.1c00226. eCollection 2021 Dec 10. ACS Pharmacol Transl Sci. 2021. PMID: 34927015 Free PMC article.
Functional diversification of cerato-platanins in Moniliophthora perniciosa as seen by differential expression and protein function specialization.
de O Barsottini MR, de Oliveira JF, Adamoski D, Teixeira PJ, do Prado PF, Tiezzi HO, Sforça ML, Cassago A, Portugal RV, de Oliveira PS, de M Zeri AC, Dias SM, Pereira GA, Ambrosio AL. de O Barsottini MR, et al. Among authors: ambrosio al. Mol Plant Microbe Interact. 2013 Nov;26(11):1281-93. doi: 10.1094/MPMI-05-13-0148-R. Mol Plant Microbe Interact. 2013. PMID: 23902259 Free article.
Architecture and regulation of filamentous human cystathionine beta-synthase.
McCorvie TJ, Adamoski D, Machado RAC, Tang J, Bailey HJ, Ferreira DSM, Strain-Damerell C, Baslé A, Ambrosio ALB, Dias SMG, Yue WW. McCorvie TJ, et al. Among authors: ambrosio alb. Nat Commun. 2024 Apr 4;15(1):2931. doi: 10.1038/s41467-024-46864-x. Nat Commun. 2024. PMID: 38575566 Free PMC article.
Allele-Specific Reprogramming of Cancer Metabolism by the Long Non-coding RNA CCAT2.
Redis RS, Vela LE, Lu W, Ferreira de Oliveira J, Ivan C, Rodriguez-Aguayo C, Adamoski D, Pasculli B, Taguchi A, Chen Y, Fernandez AF, Valledor L, Van Roosbroeck K, Chang S, Shah M, Kinnebrew G, Han L, Atlasi Y, Cheung LH, Huang GY, Monroig P, Ramirez MS, Catela Ivkovic T, Van L, Ling H, Gafà R, Kapitanovic S, Lanza G, Bankson JA, Huang P, Lai SY, Bast RC, Rosenblum MG, Radovich M, Ivan M, Bartholomeusz G, Liang H, Fraga MF, Widger WR, Hanash S, Berindan-Neagoe I, Lopez-Berestein G, Ambrosio ALB, Gomes Dias SM, Calin GA. Redis RS, et al. Mol Cell. 2016 Feb 18;61(4):520-534. doi: 10.1016/j.molcel.2016.01.015. Epub 2016 Feb 4. Mol Cell. 2016. PMID: 26853146 Free PMC article.
74 results