Liu Y - Search Results

1

An interdomain interaction of the androgen receptor is required for its aggregation and toxicity in spinal and bulbar muscular atrophy.

Orr CR, Montie HL, Liu Y, Bolzoni E, Jenkins SC, Wilson EM, Joseph JD, McDonnell DP, Merry DE. Orr CR, et al. Among authors: liu y. J Biol Chem. 2010 Nov 12;285(46):35567-77. doi: 10.1074/jbc.M110.146845. Epub 2010 Sep 8. J Biol Chem. 2010. PMID: 20826791 Free PMC article.

2

Cytoplasmic retention of polyglutamine-expanded androgen receptor ameliorates disease via autophagy in a mouse model of spinal and bulbar muscular atrophy.

Montie HL, Cho MS, Holder L, Liu Y, Tsvetkov AS, Finkbeiner S, Merry DE. Montie HL, et al. Among authors: liu y. Hum Mol Genet. 2009 Jun 1;18(11):1937-50. doi: 10.1093/hmg/ddp115. Epub 2009 Mar 11. Hum Mol Genet. 2009. PMID: 19279159 Free PMC article.

3

FOXO3a is broadly neuroprotective in vitro and in vivo against insults implicated in motor neuron diseases.

Mojsilovic-Petrovic J, Nedelsky N, Boccitto M, Mano I, Georgiades SN, Zhou W, Liu Y, Neve RL, Taylor JP, Driscoll M, Clardy J, Merry D, Kalb RG. Mojsilovic-Petrovic J, et al. Among authors: liu y. J Neurosci. 2009 Jun 24;29(25):8236-47. doi: 10.1523/JNEUROSCI.1805-09.2009. J Neurosci. 2009. PMID: 19553463 Free PMC article.

4

Preventing the Androgen Receptor N/C Interaction Delays Disease Onset in a Mouse Model of SBMA.

Zboray L, Pluciennik A, Curtis D, Liu Y, Berman-Booty LD, Orr C, Kesler CT, Berger T, Gioeli D, Paschal BM, Merry DE. Zboray L, et al. Among authors: liu y. Cell Rep. 2015 Dec 15;13(10):2312-23. doi: 10.1016/j.celrep.2015.11.019. Epub 2015 Dec 7. Cell Rep. 2015. PMID: 26673324 Free PMC article.

5

The polyglutamine-expanded androgen receptor responsible for spinal and bulbar muscular atrophy inhibits the APC/C(Cdh1) ubiquitin ligase complex.

Bott LC, Salomons FA, Maric D, Liu Y, Merry D, Fischbeck KH, Dantuma NP. Bott LC, et al. Among authors: liu y. Sci Rep. 2016 Jun 17;6:27703. doi: 10.1038/srep27703. Sci Rep. 2016. PMID: 27312068 Free PMC article.

6

The 11S Proteasomal Activator REGγ Impacts Polyglutamine-Expanded Androgen Receptor Aggregation and Motor Neuron Viability through Distinct Mechanisms.

Yersak JM, Montie HL, Chevalier-Larsen ES, Liu Y, Huang L, Rechsteiner M, Merry DE. Yersak JM, et al. Among authors: liu y. Front Mol Neurosci. 2017 May 24;10:159. doi: 10.3389/fnmol.2017.00159. eCollection 2017. Front Mol Neurosci. 2017. PMID: 28596723 Free PMC article.

7

Fluorescence Imaging of Huntingtin mRNA Knockdown.

Oh E, Liu Y, Sonar MV, Merry DE, Wickstrom E. Oh E, et al. Among authors: liu y. Bioconjug Chem. 2018 Apr 18;29(4):1276-1282. doi: 10.1021/acs.bioconjchem.8b00048. Epub 2018 Feb 26. Bioconjug Chem. 2018. PMID: 29451775

8

Deubiquitinase USP7 contributes to the pathogenicity of spinal and bulbar muscular atrophy.

Pluciennik A, Liu Y, Molotsky E, Marsh GB, Ranxhi B, Arnold FJ, St-Cyr S, Davidson B, Pourshafie N, Lieberman AP, Gu W, Todi SV, Merry DE. Pluciennik A, et al. Among authors: liu y. J Clin Invest. 2021 Jan 4;131(1):e134565. doi: 10.1172/JCI134565. J Clin Invest. 2021. PMID: 33170804 Free PMC article.

9

Neuromuscular junction pathology is correlated with differential motor unit vulnerability in spinal and bulbar muscular atrophy.

Molotsky E, Liu Y, Lieberman AP, Merry DE. Molotsky E, et al. Among authors: liu y. Acta Neuropathol Commun. 2022 Jul 5;10(1):97. doi: 10.1186/s40478-022-01402-y. Acta Neuropathol Commun. 2022. PMID: 35791011 Free PMC article.

10

Differentially disrupted spinal cord and muscle energy metabolism in spinal and bulbar muscular atrophy.

DeBartolo D, Arnold FJ, Liu Y, Molotsky E, Tang HY, Merry DE. DeBartolo D, et al. Among authors: liu y. JCI Insight. 2024 Mar 5;9(7):e178048. doi: 10.1172/jci.insight.178048. JCI Insight. 2024. PMID: 38452174 Free PMC article.

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