Brown EM - Search Results

1

Calmodulin regulates Ca2+-sensing receptor-mediated Ca2+ signaling and its cell surface expression.

Huang Y, Zhou Y, Wong HC, Castiblanco A, Chen Y, Brown EM, Yang JJ. Huang Y, et al. Among authors: brown em. J Biol Chem. 2010 Nov 12;285(46):35919-31. doi: 10.1074/jbc.M110.147918. Epub 2010 Sep 8. J Biol Chem. 2010. PMID: 20826781 Free PMC article.

2

Identification and dissection of Ca(2+)-binding sites in the extracellular domain of Ca(2+)-sensing receptor.

Huang Y, Zhou Y, Yang W, Butters R, Lee HW, Li S, Castiblanco A, Brown EM, Yang JJ. Huang Y, et al. Among authors: brown em. J Biol Chem. 2007 Jun 29;282(26):19000-10. doi: 10.1074/jbc.M701096200. Epub 2007 May 3. J Biol Chem. 2007. PMID: 17478419 Free PMC article.

3

Multiple Ca(2+)-binding sites in the extracellular domain of the Ca(2+)-sensing receptor corresponding to cooperative Ca(2+) response.

Huang Y, Zhou Y, Castiblanco A, Yang W, Brown EM, Yang JJ. Huang Y, et al. Among authors: brown em. Biochemistry. 2009 Jan 20;48(2):388-98. doi: 10.1021/bi8014604. Biochemistry. 2009. PMID: 19102677 Free PMC article.

4

Elucidation of a novel extracellular calcium-binding site on metabotropic glutamate receptor 1{alpha} (mGluR1{alpha}) that controls receptor activation.

Jiang Y, Huang Y, Wong HC, Zhou Y, Wang X, Yang J, Hall RA, Brown EM, Yang JJ. Jiang Y, et al. Among authors: brown em. J Biol Chem. 2010 Oct 22;285(43):33463-33474. doi: 10.1074/jbc.M110.147033. Epub 2010 Aug 12. J Biol Chem. 2010. PMID: 20705606 Free PMC article.

5

Extracellular calcium modulates actions of orthosteric and allosteric ligands on metabotropic glutamate receptor 1α.

Jiang JY, Nagaraju M, Meyer RC, Zhang L, Hamelberg D, Hall RA, Brown EM, Conn PJ, Yang JJ. Jiang JY, et al. Among authors: brown em. J Biol Chem. 2014 Jan 17;289(3):1649-61. doi: 10.1074/jbc.M113.507665. Epub 2013 Nov 26. J Biol Chem. 2014. PMID: 24280223 Free PMC article.

6

Identification of an L-phenylalanine binding site enhancing the cooperative responses of the calcium-sensing receptor to calcium.

Zhang C, Huang Y, Jiang Y, Mulpuri N, Wei L, Hamelberg D, Brown EM, Yang JJ. Zhang C, et al. Among authors: brown em. J Biol Chem. 2014 Feb 21;289(8):5296-309. doi: 10.1074/jbc.M113.537357. Epub 2014 Jan 6. J Biol Chem. 2014. PMID: 24394414 Free PMC article.

7

Direct determination of multiple ligand interactions with the extracellular domain of the calcium-sensing receptor.

Zhang C, Zhuo Y, Moniz HA, Wang S, Moremen KW, Prestegard JH, Brown EM, Yang JJ. Zhang C, et al. Among authors: brown em. J Biol Chem. 2014 Nov 28;289(48):33529-42. doi: 10.1074/jbc.M114.604652. Epub 2014 Oct 10. J Biol Chem. 2014. PMID: 25305020 Free PMC article.

8

The calcium sensing receptor: from calcium sensing to signaling.

Zhang C, Miller CL, Brown EM, Yang JJ. Zhang C, et al. Among authors: brown em. Sci China Life Sci. 2015 Jan;58(1):14-27. doi: 10.1007/s11427-014-4779-y. Epub 2015 Jan 10. Sci China Life Sci. 2015. PMID: 25576451 Free article. Review.

9

Role of Ca2+ and L-Phe in regulating functional cooperativity of disease-associated "toggle" calcium-sensing receptor mutations.

Zhang C, Mulpuri N, Hannan FM, Nesbit MA, Thakker RV, Hamelberg D, Brown EM, Yang JJ. Zhang C, et al. Among authors: brown em. PLoS One. 2014 Nov 24;9(11):e113622. doi: 10.1371/journal.pone.0113622. eCollection 2014. PLoS One. 2014. PMID: 25420019 Free PMC article.

10

Structural basis for regulation of human calcium-sensing receptor by magnesium ions and an unexpected tryptophan derivative co-agonist.

Zhang C, Zhang T, Zou J, Miller CL, Gorkhali R, Yang JY, Schilmiller A, Wang S, Huang K, Brown EM, Moremen KW, Hu J, Yang JJ. Zhang C, et al. Among authors: brown em. Sci Adv. 2016 May 27;2(5):e1600241. doi: 10.1126/sciadv.1600241. eCollection 2016 May. Sci Adv. 2016. PMID: 27386547 Free PMC article.

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