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Rational design, synthesis and testing of novel tricyclic topoisomerase inhibitors for the treatment of bacterial infections part 2.
Kirk R, Ratcliffe A, Noonan G, Uosis-Martin M, Lyth D, Bardell-Cox O, Massam J, Schofield P, Lyons A, Clare D, Maclean J, Smith A, Savage V, Mohmed S, Charrier C, Salisbury AM, Moyo E, Ooi N, Chalam-Judge N, Cheung J, Stokes NR, Best S, Craighead M, Armer R, Huxley A. Kirk R, et al. Among authors: massam j. RSC Med Chem. 2020 Sep 18;11(12):1379-1385. doi: 10.1039/d0md00175a. eCollection 2020 Dec 17. RSC Med Chem. 2020. PMID: 34095845 Free PMC article.
Rational design, synthesis and testing of novel tricyclic topoisomerase inhibitors for the treatment of bacterial infections part 1.
Kirk R, Ratcliffe A, Noonan G, Uosis-Martin M, Lyth D, Bardell-Cox O, Massam J, Schofield P, Hindley S, Jones DR, Maclean J, Smith A, Savage V, Mohmed S, Charrier C, Salisbury AM, Moyo E, Metzger R, Chalam-Judge N, Cheung J, Stokes NR, Best S, Craighead M, Armer R, Huxley A. Kirk R, et al. Among authors: massam j. RSC Med Chem. 2020 Sep 18;11(12):1366-1378. doi: 10.1039/d0md00174k. eCollection 2020 Dec 17. RSC Med Chem. 2020. PMID: 34095844 Free PMC article.
Scalable nanoprecipitation of niclosamide and in vivo demonstration of long-acting delivery after intramuscular injection.
Hobson JJ , Savage AC , Dwyer AB , Unsworth C , Massam J , Arshad U , Pertinez H , Box H , Tatham L , Rajoli RKR , Neary M , Sharp J , Valentijn A , David C , Curley P , Liptrott NJ , McDonald TO , Owen A , Rannard SP . Hobson JJ , et al. Among authors: massam j. Nanoscale. 2021 Apr 7;13(13):6410-6416. doi: 10.1039/d1nr00309g. Epub 2021 Mar 25. Nanoscale. 2021. PMID: 33885522