Ostrand-Rosenberg S - Search Results

1

Alternative Ii-independent antigen-processing pathway in leukemic blasts involves TAP-dependent peptide loading of HLA class II complexes.

van Luijn MM, Chamuleau ME, Ressing ME, Wiertz EJ, Ostrand-Rosenberg S, Souwer Y, Zevenbergen A, Ossenkoppele GJ, van de Loosdrecht AA, van Ham SM. van Luijn MM, et al. Cancer Immunol Immunother. 2010 Dec;59(12):1825-38. doi: 10.1007/s00262-010-0908-z. Epub 2010 Sep 5. Cancer Immunol Immunother. 2010. PMID: 20820776 Free PMC article.

2

The absence of invariant chain in MHC II cancer vaccines enhances the activation of tumor-reactive type 1 CD4+ T lymphocytes.

Thompson JA, Srivastava MK, Bosch JJ, Clements VK, Ksander BR, Ostrand-Rosenberg S. Thompson JA, et al. Cancer Immunol Immunother. 2008 Mar;57(3):389-98. doi: 10.1007/s00262-007-0381-5. Epub 2007 Aug 28. Cancer Immunol Immunother. 2008. PMID: 17724589 Free PMC article.

3

Lung cancer patients' CD4(+) T cells are activated in vitro by MHC II cell-based vaccines despite the presence of myeloid-derived suppressor cells.

Srivastava MK, Bosch JJ, Thompson JA, Ksander BR, Edelman MJ, Ostrand-Rosenberg S. Srivastava MK, et al. Cancer Immunol Immunother. 2008 Oct;57(10):1493-504. doi: 10.1007/s00262-008-0490-9. Epub 2008 Mar 6. Cancer Immunol Immunother. 2008. PMID: 18322683 Free PMC article.

4

Uveal melanoma cell-based vaccines express MHC II molecules that traffic via the endocytic and secretory pathways and activate CD8+ cytotoxic, tumor-specific T cells.

Bosch JJ, Iheagwara UK, Reid S, Srivastava MK, Wolf J, Lotem M, Ksander BR, Ostrand-Rosenberg S. Bosch JJ, et al. Cancer Immunol Immunother. 2010 Jan;59(1):103-12. doi: 10.1007/s00262-009-0729-0. Epub 2009 Jun 26. Cancer Immunol Immunother. 2010. PMID: 19557412 Free PMC article.

5

Class II-associated invariant chain peptide down-modulation enhances the immunogenicity of myeloid leukemic blasts resulting in increased CD4+ T-cell responses.

van Luijn MM, Chamuleau ME, Thompson JA, Ostrand-Rosenberg S, Westers TM, Souwer Y, Ossenkoppele GJ, van Ham SM, van de Loosdrecht AA. van Luijn MM, et al. Haematologica. 2010 Mar;95(3):485-93. doi: 10.3324/haematol.2009.010595. Epub 2009 Nov 10. Haematologica. 2010. PMID: 19903675 Free PMC article.

6

Tumor antigen presentation: changing the rules.

Armstrong TD, Pulaski BA, Ostrand-Rosenberg S. Armstrong TD, et al. Cancer Immunol Immunother. 1998 Apr;46(2):70-4. doi: 10.1007/s002620050463. Cancer Immunol Immunother. 1998. PMID: 9558001 Free PMC article. Review.

7

MHC class II and CD80 tumor cell-based vaccines are potent activators of type 1 CD4+ T lymphocytes provided they do not coexpress invariant chain.

Ilkovitch D, Ostrand-Rosenberg S. Ilkovitch D, et al. Cancer Immunol Immunother. 2004 Jun;53(6):525-32. doi: 10.1007/s00262-003-0486-4. Epub 2004 Jan 17. Cancer Immunol Immunother. 2004. PMID: 14730400 Free PMC article.

8

Myeloid-derived suppressor cells: more mechanisms for inhibiting antitumor immunity.

Ostrand-Rosenberg S. Ostrand-Rosenberg S. Cancer Immunol Immunother. 2010 Oct;59(10):1593-600. doi: 10.1007/s00262-010-0855-8. Epub 2010 Apr 23. Cancer Immunol Immunother. 2010. PMID: 20414655 Free PMC article. Review.

9

Novel strategies for inhibiting PD-1 pathway-mediated immune suppression while simultaneously delivering activating signals to tumor-reactive T cells.

Ostrand-Rosenberg S, Horn LA, Alvarez JA. Ostrand-Rosenberg S, et al. Cancer Immunol Immunother. 2015 Oct;64(10):1287-93. doi: 10.1007/s00262-015-1677-5. Epub 2015 Mar 20. Cancer Immunol Immunother. 2015. PMID: 25792524 Free PMC article. Review.

10

Class II-transfected tumor cells directly present endogenous antigen to CD4+ T cells in vitro and are APCs for tumor-encoded antigens in vivo.

Armstrong TD, Clements VK, Ostrand-Rosenberg S. Armstrong TD, et al. J Immunother. 1998 May;21(3):218-24. doi: 10.1097/00002371-199805000-00008. J Immunother. 1998. PMID: 9610914

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