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Control of mammary tumor differentiation by SKI-606 (bosutinib).
Hebbard L, Cecena G, Golas J, Sawada J, Ellies LG, Charbono A, Williams R, Jimenez RE, Wankell M, Arndt KT, DeJoy SQ, Rollins RA, Diesl V, Follettie M, Chen L, Rosfjord E, Cardiff RD, Komatsu M, Boschelli F, Oshima RG. Hebbard L, et al. Among authors: sawada j. Oncogene. 2011 Jan 20;30(3):301-12. doi: 10.1038/onc.2010.412. Epub 2010 Sep 6. Oncogene. 2011. PMID: 20818417 Free PMC article.
Prolonged activation of cAMP signaling leads to endothelial barrier disruption via transcriptional repression of RRAS.
Perrot CY, Sawada J, Komatsu M. Perrot CY, et al. Among authors: sawada j. FASEB J. 2018 May 18;32(11):fj201700818RRR. doi: 10.1096/fj.201700818RRR. Online ahead of print. FASEB J. 2018. PMID: 29775418 Free PMC article.
Our study demonstrated that, contrary to the widely accepted notion, cAMP elevation in endothelial cells ultimately increases vascular permeability, and the cAMP-dependent RRAS repression critically contributes to this effect.-Perrot, C. Y., Sawada, J., Komatsu, M. …
Our study demonstrated that, contrary to the widely accepted notion, cAMP elevation in endothelial cells ultimately increases vascular perme …
Normalization of tumor vasculature by R-Ras.
Sawada J, Komatsu M. Sawada J, et al. Cell Cycle. 2012 Dec 1;11(23):4285-6. doi: 10.4161/cc.22465. Epub 2012 Oct 24. Cell Cycle. 2012. PMID: 23095670 Free PMC article. No abstract available.
MicroRNA-211 Modulates the DUSP6-ERK5 Signaling Axis to Promote BRAFV600E-Driven Melanoma Growth In Vivo and BRAF/MEK Inhibitor Resistance.
Lee B, Sahoo A, Sawada J, Marchica J, Sahoo S, Layng FIAL, Finlay D, Mazar J, Joshi P, Komatsu M, Vuori K, de Jong PR, Ray A, Perera RJ. Lee B, et al. Among authors: sawada j. J Invest Dermatol. 2021 Feb;141(2):385-394. doi: 10.1016/j.jid.2020.06.038. Epub 2020 Sep 2. J Invest Dermatol. 2021. PMID: 32888955 Free PMC article.
452 results