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Control of mammary tumor differentiation by SKI-606 (bosutinib).
Hebbard L, Cecena G, Golas J, Sawada J, Ellies LG, Charbono A, Williams R, Jimenez RE, Wankell M, Arndt KT, DeJoy SQ, Rollins RA, Diesl V, Follettie M, Chen L, Rosfjord E, Cardiff RD, Komatsu M, Boschelli F, Oshima RG. Hebbard L, et al. Among authors: boschelli f. Oncogene. 2011 Jan 20;30(3):301-12. doi: 10.1038/onc.2010.412. Epub 2010 Sep 6. Oncogene. 2011. PMID: 20818417 Free PMC article.
Efficacy and pharmacodynamic effects of bosutinib (SKI-606), a Src/Abl inhibitor, in freshly generated human pancreas cancer xenografts.
Messersmith WA, Rajeshkumar NV, Tan AC, Wang XF, Diesl V, Choe SE, Follettie M, Coughlin C, Boschelli F, Garcia-Garcia E, Lopez-Rios F, Jimeno A, Hidalgo M. Messersmith WA, et al. Among authors: boschelli f. Mol Cancer Ther. 2009 Jun;8(6):1484-93. doi: 10.1158/1535-7163.MCT-09-0075. Epub 2009 Jun 9. Mol Cancer Ther. 2009. PMID: 19509264
SKI-606, a Src/Abl inhibitor with in vivo activity in colon tumor xenograft models.
Golas JM, Lucas J, Etienne C, Golas J, Discafani C, Sridharan L, Boghaert E, Arndt K, Ye F, Boschelli DH, Li F, Titsch C, Huselton C, Chaudhary I, Boschelli F. Golas JM, et al. Among authors: boschelli dh, boschelli f. Cancer Res. 2005 Jun 15;65(12):5358-64. doi: 10.1158/0008-5472.CAN-04-2484. Cancer Res. 2005. PMID: 15958584
SKI-606, a 4-anilino-3-quinolinecarbonitrile dual inhibitor of Src and Abl kinases, is a potent antiproliferative agent against chronic myelogenous leukemia cells in culture and causes regression of K562 xenografts in nude mice.
Golas JM, Arndt K, Etienne C, Lucas J, Nardin D, Gibbons J, Frost P, Ye F, Boschelli DH, Boschelli F. Golas JM, et al. Among authors: boschelli dh, boschelli f. Cancer Res. 2003 Jan 15;63(2):375-81. Cancer Res. 2003. PMID: 12543790
4-Anilino-7-pyridyl-3-quinolinecarbonitriles as Src kinase inhibitors.
Zhang N, Wu B, Boschelli DH, Golas JM, Boschelli F. Zhang N, et al. Among authors: boschelli dh, boschelli f. Bioorg Med Chem Lett. 2009 Sep 1;19(17):5071-4. doi: 10.1016/j.bmcl.2009.07.043. Epub 2009 Jul 10. Bioorg Med Chem Lett. 2009. PMID: 19632113
Osteogenic effects of a potent Src-over-Abl-selective kinase inhibitor in the mouse.
Murrills RJ, Fukayama S, Boschelli F, Matteo JJ, Owens J, Golas JM, Patel D, Lane G, Liu YB, Carter L, Jussif J, Spaulding V, Wang YD, Boschelli DH, McKew JC, Li XJ, Lockhead S, Milligan C, Kharode YP, Diesl V, Bai Y, Follettie M, Bex FJ, Komm B, Bodine PV. Murrills RJ, et al. Among authors: boschelli f. J Pharmacol Exp Ther. 2012 Mar;340(3):676-87. doi: 10.1124/jpet.111.185793. Epub 2011 Dec 9. J Pharmacol Exp Ther. 2012. PMID: 22171089
61 results