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The exon junction complex differentially marks spliced junctions.
Saulière J, Haque N, Harms S, Barbosa I, Blanchette M, Le Hir H. Saulière J, et al. Among authors: le hir h. Nat Struct Mol Biol. 2010 Oct;17(10):1269-71. doi: 10.1038/nsmb.1890. Epub 2010 Sep 5. Nat Struct Mol Biol. 2010. PMID: 20818392
A UPF3-mediated regulatory switch that maintains RNA surveillance.
Chan WK, Bhalla AD, Le Hir H, Nguyen LS, Huang L, Gécz J, Wilkinson MF. Chan WK, et al. Among authors: le hir h. Nat Struct Mol Biol. 2009 Jul;16(7):747-53. doi: 10.1038/nsmb.1612. Epub 2009 Jun 7. Nat Struct Mol Biol. 2009. PMID: 19503078
Proteins associated with the exon junction complex also control the alternative splicing of apoptotic regulators.
Michelle L, Cloutier A, Toutant J, Shkreta L, Thibault P, Durand M, Garneau D, Gendron D, Lapointe E, Couture S, Le Hir H, Klinck R, Elela SA, Prinos P, Chabot B. Michelle L, et al. Among authors: le hir h. Mol Cell Biol. 2012 Mar;32(5):954-67. doi: 10.1128/MCB.06130-11. Epub 2011 Dec 27. Mol Cell Biol. 2012. PMID: 22203037 Free PMC article.
Perispeckles are major assembly sites for the exon junction core complex.
Daguenet E, Baguet A, Degot S, Schmidt U, Alpy F, Wendling C, Spiegelhalter C, Kessler P, Rio MC, Le Hir H, Bertrand E, Tomasetto C. Daguenet E, et al. Among authors: le hir h. Mol Biol Cell. 2012 May;23(9):1765-82. doi: 10.1091/mbc.E12-01-0040. Epub 2012 Mar 14. Mol Biol Cell. 2012. PMID: 22419818 Free PMC article.
65 results