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The IP(3) receptor-mitochondria connection in apoptosis and autophagy.
Decuypere JP, Monaco G, Bultynck G, Missiaen L, De Smedt H, Parys JB. Decuypere JP, et al. Among authors: monaco g. Biochim Biophys Acta. 2011 May;1813(5):1003-13. doi: 10.1016/j.bbamcr.2010.11.023. Epub 2010 Dec 10. Biochim Biophys Acta. 2011. PMID: 21146562 Free article. Review.
IP3R2 levels dictate the apoptotic sensitivity of diffuse large B-cell lymphoma cells to an IP3R-derived peptide targeting the BH4 domain of Bcl-2.
Akl H, Monaco G, La Rovere R, Welkenhuyzen K, Kiviluoto S, Vervliet T, Molgó J, Distelhorst CW, Missiaen L, Mikoshiba K, Parys JB, De Smedt H, Bultynck G. Akl H, et al. Among authors: monaco g. Cell Death Dis. 2013 May 16;4(5):e632. doi: 10.1038/cddis.2013.140. Cell Death Dis. 2013. PMID: 23681227 Free PMC article.
The BH4 domain of anti-apoptotic Bcl-XL, but not that of the related Bcl-2, limits the voltage-dependent anion channel 1 (VDAC1)-mediated transfer of pro-apoptotic Ca2+ signals to mitochondria.
Monaco G, Decrock E, Arbel N, van Vliet AR, La Rovere RM, De Smedt H, Parys JB, Agostinis P, Leybaert L, Shoshan-Barmatz V, Bultynck G. Monaco G, et al. J Biol Chem. 2015 Apr 3;290(14):9150-61. doi: 10.1074/jbc.M114.622514. Epub 2015 Feb 13. J Biol Chem. 2015. PMID: 25681439 Free PMC article.
529 results